Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"metabolic imbalance"”.
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Metabolic and functional approaches to investigate the effects of cytokines on the physiology of in-vitro and in-vivo models of diabetic retinopathy
… Several studies have reported that metabolic and functional dysregulation in the retina precedes the development of vascular damage in DR. However, current treatment strategies are aimed at treating the late stage sight-threatening vascular problems and do not prevent DR progression. …
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Cigarette Smoke Exposure in Drosophila Reveals Wnt-Mediated Remodeling of Airway Structure and Systemic Physiology
… shortened lifespan, impaired locomotor activity, metabolic imbalance, increased apoptosis of tracheal epithelial cells, and disrupted tracheal architecture. Using tracheal-specific genetic manipulations, we systematically examined the effects of canonical Wnt/β-catenin signaling and non-canonical …
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The Role of Oxygen and Oxygen-Dependent Enzymes in Protein Folding, Metabolism, and Redox Homeostasis
… of an oxygen dependent enzyme may elicit a metabolic imbalance leading to loss of redox homeostasis. Taken together, this thesis explores the role and the importance of oxygen and oxygen dependent enzymes that drive acute responses such as affecting the disulfide bond formation of protein …
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Adapt, Survive or Die - Metabolic Imbalances and the Enteric Nervous System
… of obesity/type 2-diabetes (T2D) related metabolic imbalances? Or do they die?” are asked. Obese and T2D patients have high rates of gastrointestinal (GI) symptoms. The GI tract comprises the body’s largest surface to the outside environment; it performs diverse and complex roles in an …
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La Metabolomica: una nuova era in Cardiologia. Le nostre esperienze originali nei campi dell' insufficienza cardiaca, della cardiopatia ischemica e dell' ipertensione polmonare
… of a broad range of metabolites providing a metabolic picture able to identify metabolic changes. On these basis we carried out a metabolomics on three settings of cardiovascular diseases: a) heart failure; b) Stable coronary artery disease; c) Pulmonary hypertension in systemic sclerosis. …