Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 27 for “"metabolic energy"”.
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Evaluation of Metabolic Energy Expenditure During Prolonged Steady-State Exercise
Energy consumed during prolonged steady state exercise was partitioned to radiant, convective and evaporative heat and the energy for climbing and walking. Healthy, non-obese subjects, ages 20 to 35 years, were classified as 5 active males, 5 trained males, 5 active females and 5 trained females. …
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Oxidative Inactivation of Bacillus Subtilis Aspartate Transcarbamylase in Vitro
… requires the continuous generation of metabolic energy, but not nucleic acid or protein synthesis. Immunochemical studies indicated that ATCase is degraded simultaneously with inactivation in vivo.
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Efficiency and Motor Skill Learning (Locomotion, Physical, Physiology, Evolution, Practice)
… limb segments, based on a link segment model, to metabolic energy expenditure measured using indirect calorimetry. A repeated measures ANOVA showed a significant increase in transport efficiency but no reliable change in E% after 20 3 min trials. Nevertheless, there was an overall improvement in …
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A Study of the Inactivation in Vivo of the Luciferase in the Luminous Marine Bacterium Beneckea Harveyi
… Through studies utilizing inhibitors of metabolic energy production, an inhibitor of protein synthesis, and a mutant in which the luciferase was inactivated at a much slower rate, and through studies of intracellular ATP levels under various conditions, a model for the modulation of …
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On the mechanisms of transport and energy coupling in ABC exporters
… by ABC transporters, the mechanisms by which metabolic energy is coupled to the transport cycle is still elusive. This thesis presents a series of functional studies using whole cells as well as artificial phospholipid membranes to study the energetics of transport, and the influence of …
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Profiling the neurovascular cell interactions in alcohol exposure and HIV-1 infection
… HIV-1 transmission, infection, and the role of metabolic energy imbalance during NeuroAIDS progression, which will enable me to formulate the possible mechanism for NeuroAIDS progression. The second aim will help me establish the technique of rat embryonic neuronal isolation, which will be used …
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A knee brace design to reduce the energy consumption of walking
… could be created which dramatically reduces the metabolic energy used in walking especially when the wearer is carrying additional torso weight. Target population groups include military personnel who must carry heavy battle packs and body armor, hikers, letter carriers, and the quasi disabled. …
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ON THE METABOLIC AND MECHANICAL DEMANDS OF WALKING: THE EFFECTS OF SLIDING FRICTION, LIMB SWING WORK, AND BOUT DURATION.
Researchers have long investigated the metabolic and mechanical demands of locomotion. Discoveries in such field not only have advanced our understanding of the physiology of movement and energy transformations, but have also impacted anthropology, zoology, sports science, and clinical medicine. …
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Achieving Near-Natural Locomotion in Transfemoral Amputees - A Control Theoretic Approach
… gait, such as lower walking speed, increased metabolic energy expenditure, and reduced power in the amputated limb during the push-off phase. For above-knee amputations, where the individual loses both the knee and ankle joints, the effects are more severe. Losing multiple joints leads to …
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Autonomous powered exoskeleton to improve the efficiency of human walking
… autonomous leg exoskeletons that reduce the metabolic energy consumed when humans walk and run, but such technologies have traditionally remained unachievable. In this thesis, I present the Augmentation Factor, a simple model that predicts the metabolic impact of lower limb exoskeletons …
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Biochemical changes associated with embryonic and larval development in the American lobster Homarus americanus Milne Edwards
… triacylglycerol supplied most of the energy and the fatty acid 20:5 was selectively utilized. Absence of prolonged cold incubation temperatures resulted in increased yolk reserves in newly hatched larvae. Weight, ash, protein, carbohydrate and lipid varied in association with the …
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A Role for the HSV Tegument Protein pUL16 in Modulating Cellular Energy Metabolism during HSV-2 Infection
… the influence of pUL16 on host cell energy metabolism by quantifying parameters of mitochondrial morphology, oxidative phosphorylation, glycolysis and ATP metabolism, in mock, HSV-2 WT and HSV-2 pUL16 null mutant (Δ16), infected human keratinocytes (HaCaT). Mitochondria in WT infected …
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Frontal Plane Pelvic Drop in Runners: Causes and Clinical Implications
… between frontal plane pelvic drop and increased metabolic energy demands. Subjects were recreational runners who ran an average of five or more miles per week. Data from an initial ten subjects were collected, followed by an additional eleven subjects tested for Specific Aims #1, 2, and 3. GM …
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Optimizing Shoe Midsoles for Running Performance
… at a given speed, because it compares the input (metabolic) energy to the output (kinetic) energy. Running economy data is collected in highly controlled environments by using gas exchange measurement systems often in the form of wearable masks for runners on treadmills. The process of …
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Regulation of the catalytic and allosteric properties of photoreceptor phosphodiesterase (PDE6) by the glutamic acid-rich protein-2 (GARP2)
… noise", enhance its sensitivity and conserve metabolic energy during rod photoresponse saturation.</p><p>The first aim of this research is to better understand the unique biochemical and biophysical characteristics of GARP2 in order to reveal its functional attributes for regulating PDE6 …
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Root-zone temperature effects on the nutrient uptake of horticultural crops
… to 36C RZT appeared to deplete available metabolic energy for growth and nutrient acquisition. The decrease in respiration after 8 days also was probably in response to depletion of carbohydrates and/or inactivation of respiratory enzymes.</p>
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Effects of carnitine on medium-chain fatty acid metabolism in newborn pigs
… MCFA oxidation provided more than 20% of the metabolic energy (increase = 0.16$\cdot$(fatty acid oxidation rate $-$ 18), r = 0.74, p $<$.01). In addition, in 18 of these pigs, dicarboxylic acid (DCA, analyzed using HPLC) excretion in urine (collected via a bladder catheter inserted via the …
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Design and evaluation of a biomimetic agonist-antagonist active knee prosthesis
… asymmetry, decreased walking speeds and high metabolic energy costs are some of the main challenges requiring the development of a new kind of prosthetic device. These challenges point to the need for highly versatile, fully integrated lower-extremity powered prostheses that can replicate the …
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Investigating the substrate binding mechanism of the mitochondrial ADP/ATP carrier
… the mitochondrial inner membrane, providing metabolic energy for the cell. Crystal structures of the inhibited cytoplasmic-open and matrix-open states support an alternating access mechanism, involving a cytoplasmic and a matrix gate. However, the molecular nature of substrate binding remains …
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Elevated Cochlear Adenosine Causes Hearing Loss Via Adora2B Signaling
… HL is often attributed to a disruption in this metabolic energy currency. Patients who lack adenosine deaminase (ADA), the enzyme that irreversibly metabolizes adenosine, have high levels of adenosine that yield severe health problems, including HL; however, the pathogenic mechanisms behind HL …
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