Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 72 for “"metabolic control"”.
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Metabolic Control Analysis of Carbon Pathways
In a complex metabolic system, collective behaviors can emerge which are not obvious consequences of the individual components, because each of the components interacts with others in unpredictable ways. In the particular case of carbon metabolism, the emergent condition of this complex interaction …
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Factors affecting metabolism and metabolic control in phenylketonuria
Phenylketonuria (PKU) is an inherited metabolic disorder treated by a phenylalanine restricted diet in order to avoid neurocognitive impairment. Blood phenylalanine is the main outcome marker which is modulated by many dietary factors. Traditionally, L-amino acid-based protein substitutes are the …
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Type 2 Diabetes And Insomnia: Impact On Metabolic Control
… of the quantity and quality of sleep to glycemic control in type 2 diabetics. No research on the impact of insomnia on diabetes prevention and/or management was found in the literature. The purpose of this 11 week intervention study was to examine the effects of participation in Cognitive …
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Metabolic control of immune cell fate by hypoxia-inducible factors
… considering a key aspect of HIF activity: i) the metabolic consequence of transcriptional activity downstream of HIF and ii) the metabolic control of the regulators lying upstream of HIF. Chapter 2 describes the discovery of HIF1-dependent modulation of vitamin B6 metabolism via pyridoxal …
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Metabolic control of the ethylmalonyl-CoA pathway in Methylobacterium extorquens AM1
… ethylmalonyl-CoA pathway was investigated for a metabolic control point taking advantage of growth on ethylamine, a two-carbon substrate that is converted to biomass precursors through the ethylmalonyl-CoA pathway. Using a two-carbon substrate successfully bypassed identified regulatory …
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Parental Memory Predictors of Children's Daily Diabetes Management and Metabolic Control
… memory and children's diabetes behaviors and metabolic control. Data revealed that parental memory and responsibility predicted children's percentage of calories from fat and carbohydrates, and metabolic control, accounting for 7.3% of the variance in calories from fat and 18.5% of the …
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BEYOND CHEMICAL SIGNALING: MECHANICAL FORCES AS DRIVERS OF MITOTIC AND METABOLIC CONTROL
… determinant for cell fate and health. Metabolic regulation and mitosis are among the most essential processes carried out by the cell. Although both have been extensively characterized biochemically and genetically, less is known about their mechanics and the central role played by …
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Diabetes in Latinas : Depression, Metabolic Control, and the Roles of Acculturation and Social Support
… and among diabetes, depression, social support, metabolic control and acculturation. Ninety-six participants from a large publicly funded teaching hospital's community clinic took part in a brief interview that involved demographic questions, a depression screening toll, a measure for Latino and …
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A behavioral family intervention to improve adherence and metabolic control in children with IDDM
… behavioral family intervention on adherence and metabolic control in insulin dependent diabetic children (IODM). Specifically, assumption of regimen responsibilities between the parent and child were manipulated to facilitate regimen adherence. The intervention delivered was a target-specific …
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Measuring insulin sensitivity and the effect of alternative dietary interventions and exercise on metabolic control
The metabolic syndrome is highly prevalent in western society, and the numbers affected by obesity and diabetes continue to rise. This thesis reviews the mechanisms at play and the gaps in the literature that, if filled, may increase knowledge of treatment regimes for affected individuals. …
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Metabolic control of neural stem cell function in a patient-derived model of multiple sclerosis
… and CS, there is growing interest in exploring metabolic pathways as potential targets for therapeutic intervention in PMS to correct dysfunctional senescence-associated phenotypes that may be contributing to neuronal loss. My research aims to investigate the role of neural stem cell (NSC) …
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BLOOD GLUCOSE MONITORING AND METABOLIC CONTROL IN YOUTH WITH TYPE 1 DIABETES: RELATION TO DISEASE CARE
… 1 diabetes (T1D) are strongly related to better metabolic control (HbA1c). However, HbA1c results are only available, on average, every three months, and may not accurately capture intricacies of blood glucose fluctuations. Youth then must rely on blood glucose levels obtained throughout the day …
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Metabolic Control, Quality of Life, and Body Image In Patients With Glycogen Storage Disease Type Ia
… health-related quality of life, body image, and metabolic control. Results found that quality of life was significantly lower than the general population on both the physical and mental component scores (t=-3.11, p=0.005; t=-2.21, p=0.03). Additionally, body image was significantly lower on all …
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Insights Into The Therapeutic Potential of Salt Inducible Kinase 1: A Novel Mechanism of Metabolic Control
… and <em>in vivo</em>, and intracellular metabolic and mitochondrial regulation by this kinase. Herein, evidence is provided demonstrating that skeletal muscle SIK1 regulates insulin sensitivity and blood glucose concentrations through mechanism(s) independent of the canonical insulin …
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The Effect of Staged Diabetes Management on Metabolic Control in Native Americans with Type II Diabetes
… the effect of Staged Diabetes Management on metabolic control in Native American patients with Type It diabetes as compared to traditional diabetes management.<br /> The experimental group consisted of 54 Native American patients with type n diabetes who were treated with Staged Diabetes …
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A RANDOMIZED STUDY OF THE GLUNOVO REAL-TIME CGM EFFECTIVENESS ON METABOLIC CONTROL IN PATIENTS WITH T2D
… (RT-CGM) system, Glunovo, in improving glycemic control and patient outcomes in individuals with poorly controlled type 2 diabetes (T2D) compared to traditional self-monitoring of blood glucose (SMBG). Research Design and Methods: This prospective, open-label, randomized controlled trial included …
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Developing a mobile application for promoting periodontal health and metabolic control in diabetic patients: testing and feasibility study
… severe periodontal disease can worsen glycaemic control. Effective management of both conditions is essential to improving overall health outcomes. Mobile health (mHealth) technologies are increasingly recognised for their potential in chronic disease management, yet their effectiveness in …
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The Relation Between Family Functioning, Health-related Quality of Life, and Metabolic Control in Children and Adolescents with Type 1 Diabetes
… functioning, health-related quality of life, and metabolic control in order to identify areas for intervention that can improve medical and psychosocial outcomes for children and adolescents with type 1 diabetes. Children (N = 45) ages 8-17, both male and female, with type 1 diabetes, along with …
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Fear of needles among children and adolescents with type 1 diabetes mellitus : relationship with metabolic control (HbA1c) and quality of life
… mellitus and its effects on the quality of metabolic control measured with haemoglobin A1c (HbA1c) and quality of life. Method: 33 patients aged 9-16 years old with type 1 diabetes mellitus were enrolled in the study as well as their primary caregiver. Patients and caregivers completed two …
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