Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"mesencephalon"”.
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Neuron-glial interactions in dendrite growth
… from cerebral cortex, retina, olfactory bulb, mesencephalon, striatum and spinal cord. Axon and dendrite outgrowth from isolated neurons was quantified using morphological and double-labeling immunohistochemical techniques at 18 hours and 1, 3 and 5 days in vitro. Neurons initially extended the …
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Neuromeric organization of the midbrain-hindbrain boundary region in zebrafish
… (mhb) region, where the juxtaposition of the mesencephalon and metencephalon gives rise to a signaling center, termed the midbrain-hindbrain or isthmic organizer. Evidence for lineage restriction boundaries in the mhb region is still controversial, with some very recent studies supporting the …
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Optimization of Cell Culture Procedures for Growing Neural Networks on Microelectrode Arrays
… disease, the newly developed procedures for mesencephalon isolation and culture on MEAs are an important research contribution.
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Quantitative Studies of the Mesencephalic Nucleus of the Trigeminus
… is a group of cells found, in the tectum of the mesencephalon and extends from the level of the posterior commissure to the level of the chief motor nucleus of the trigeminus. This investigation was a study of the responses of the cells in the mesencephalic nucleus of the cat to section of the …
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Generation of midbrain dopaminergic neurons in vivo and in vitro: the role of Neurogenin2
… neurons of the substantia nigra (SNc) in the mesencephalon are progressively eliminated. The ensuing loss of dopaminergic innervation of the basal ganglia manifests itself as severe motor deficits in PD patients. Clinical trials have shown that cell replacement therapy, where dopaminergic …
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Erstellung eines digitalen dreidimensionalen Volumenmodelles des menschlichen Hirnstammes nach dem stereotaktischen Wahrscheinlichkeitsatlanten von AFSHAR, WATKINS und YAP
… cut in a distance of 1 mm, covering the caudal mesencephalon, the pons and the medulla oblongata. Contour-drawings of 42 anatomical structures represent the 70 percent percentile of 30 examined specimen. All histologically measured structures including their reference marks were carefully …
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Development of the Mesencephalic Trigeminal Nucleus in the Zebrafish
… ganglion to cell bodies in the dorsal anterior mesencephalon, suggesting that the MTN does innervate jaw muscles in teleosts, contrary to previous studies. Molecular characterisation of the MTN in zebrafish revealed a similar expression profile as the mammalian MTN. To investigate whether MTN …
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Reziproke Transplantat-Wirt Interaktionen von dopaminergen Neuronen im Tiermodell der Parkinsonschen Krankheit
… Zellkonzentration vom fetalen ventralen Mesencephalon auf das Überleben und die Funktion der transplantierten dopaminergen Neurone untersucht. Es fand sich für niedrigere Zellkonzentrationen ein tendenziell höheres Überleben, ohne dass die Unterschiede zwischen den Konzentrationen jedoch …
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The Influence of Age, Gender, and Thiol Repletion in an In Vivo Model of Lewy Body Disorders
… Lewy pathology that developed in the ventral mesencephalon was confined to the ventral tegmental area, which is also associated with limbic functions. Furthermore, our studies are the first to show that females are more resistant to the development of α-synucleinopathy and neurodegeneration …
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Diencephalic asymmetries: morphological, immunohistochemical and ultrastructural analysis of habenular nuclei in elasmobranchs and teleosts
… that connects the telencephalon to the ventral mesencephalon (Concha M. L. and Wilson S. W., 2001). In representative species of almost all classes of Vertebrates the habenular nuclei are asymmetric, both in terms of size and of neuronal and neurochemical organization, although different types …
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Aportación a la morfogénesis encefálica en los horizontes XVI y XX de la clasificación de Streeter
… en el esbozo de la glándula pineal. c) MESENCEPHALON 17. El mesocoele ha sufrido un marcado alargamiento y estrechamiento, y es en el Horizonte XX un acueducto cerebral que conecta el tercer y cuarto ventrículos. 18. Histológicamente se aprecia a nivel del isthmus en el horizonte XX una …
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Identification of dopamine neuron progenitors in the embryonic midbrain and stem cell cultures - Studies on the role of neuronal subtype and differentiation state for cell replacemen in a rodent model of Parkinson's disease
… the dopamine producing neurons in the ventral mesencephalon (VM) progressively die and result in symptoms such as resting tremors, muscle rigidity, slowness and difficulties in initiating movements.Currently there is no cure for PD and the available drug treatments only offer symptomatic relief …
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Central Expression of Sex Steroid Receptors during the Ring Dove (Streptopeliarisoria) Breeding Cycle
… throughout the telencephalong diencephalon, and mesencephalon. Nuclear PR-ir was only localised in discrete regions of the preoptic-hypothalamus of both sexes. In the anterior and posterior hypothalamus, high density of AR-ir and PR-ir neurones was concentrated and co-localised in the nucleus …
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The tectal-isthmic loop of the chicken (Gallus gallus) in a slice preparation : electrophysiology of its elements
… it is the primary visual processing area in the mesencephalon of non-mammals. The isthmic system (nucleus parabigeminalis in mammals) is a complex of midbrain nuclei being spatially separated from the tectum. It contains three substructures having reciprocal connections with the optic tectum: the …
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The role of the dopaminergic neurotrophin growth/differentiation factor-5 in the developing rat ventral midbrain
… of the GDF-5 in the developing rat ventral mesencephalon (VM) was found to begin at E12 and peak on E14, the day that dopaminergic neurons undergo terminal differentiation. In the adult rat, GDF-5 was found to be restricted to heart and brain, being expressed in many areas of the brain, …
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Characterisation of the molecular mechanisms of dopaminergic axonal growth and their impairment in Parkinson's disease
… from the embryonic day (E) 14 rat ventral mesencephalon (VM). Finally, we show that the coexpression pattern of the STRAP and NME1, with midbrain dopaminergic neuronal markers was reduced in the PD brain. Since we establish the role of NME1 in promoting neurite growth in neuronal cells and …