Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"meningococcal vaccine"”.
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Determinants of Immunity against the Meningococcus
… colonizer of the human nasopharynx. Invasive meningococcal infections are associated with high rates of morbidity and mortality, despite the availability of effective antibiotic treatment options. Vaccination is therefor the most effective way to protect people against N. meningitidis. …
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Complement Factor H Related Proteins and their Biological Role During Bacterial Infection
… despite available polysaccharide and protein vaccines. Individuals with rare defects in the terminal complement pathway are susceptible to meningococcal disease but further genetic factors that contribute to disease susceptibility are less well understood. A genome wide association study has …
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Comparison of current evidence from randomized clinical trials and observational studies for immunogenicity in variable meningococcal C vaccine schedules in children, adolescents, and adults
… nearly all schedules, tetanus toxid (TT) carrier vaccines were more immunogenic than their diphtheria toxin mutant 197 (CRM or CRM197) protein carrier equivalents. This was less pronounced with 3 doses in infancy, and by 12 months of age antibody titers waned similarly regardless of the vaccine …
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Konstruktion und Charakterisierung von Lebendvakzine-Kandidaten auf der Basis von siaD-Deletionsmutanten von Neisseria meningitidis Serogruppe B
In der vorliegenden Dissertation wurde für die Entwicklung eines Lebendimpfstoffs zum Schutz vor Infektionen durch Neisseria meningitidis Serogruppe B zunächst ein geeigneter Impfstamm aus mehreren Neisserienstämmen der Serogruppe B, ST-32 Komplex, ausgewählt. In diesem sollte anschließend die …