Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"membrane-stabilizing"”.
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Membrane Stabilizing Copolymer Poloxamer 188 in Preclinical Models of Acute Myocardial Infarction Reperfusion
… flanked by hydrophilic end chains. Due to its membrane stabilizing and anti-coagulant properties, P188 remains a favorable agent to prevent membrane damage in several disease models including sickle cell anemia, muscular dystrophy, cardiac arrest and acute myocardial infarction. The predominant …
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Development of a Human Lung Cancer Cytochrome C-GFP Reporter Cell Line to Study Anti-cancer Drug Responses in Apoptosis Pathways
… inactivated due to the mutation of mitochondria membrane stabilizing proteins (e.g. Bcl-2, Bcl-xL). Therefore, the overall objective of this proposal was to understand the mechanism and the kinetic of cytochrome-c release from the mitochondria, so novel and improved molecular target therapies can …
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Amelioration of oxidative lung injury by antiarrhythmic agents
… and procainamide, are known to be effective membrane stabilizers. However, the mechanism of such "membrane stabilization" has not been elucidated. In the present study we found that all three drugs are powerful scavengers of hydroxyl! radical. In addition, lidocaine was found to be a quencher …
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Design and Synthesis of a Macrocyclic Phospholipid
The membrane-spanning phospholipids of the domain Archaea are postulated to provide membrane stability; this thesis reports the design and synthesis of a synthetic membrane-spanning macrocyclic lipid to test this hypothesis. Protected glutaric anhydride reacted with 10-undecyn-1-ol to produce a …