Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 89 for “"membrane transport"”.
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Quantification of membrane transport rates using optofluidics
The transport of ions and small molecules across membranes is a ubiquitous process in biological systems. Effective studies of membrane transport phenomena require suitable model membrane systems, efficient methods to quantify transport kinetics and a robust theoretical framework to derive …
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Membrane transport studies: novel methods, model systems and thermodynamics
… be used in conjunction with both simple model membranes and more complex biological membranes, namely the epidermis. From the data achieved from the cell it was possible to derive a series of equations which allowed access to thermodynamic parameters such as ?H, ?G and ?S. An extension of this …
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Application of Irreversible Thermodynamics to Biological Membrane Transport Phenomena
… of Onsager's Theory is made to biological transport phenomena. By transforming the coefficient matrix (the Onsager L matrix) to the diagonal form we obtain a new relation between the entropy production and the state parameters (flows or forces) of the system. Active transport across a …
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Engineered Cytoskeletal Arrays Reveal Mechanisms Of Membrane Transport And Tubulation
Within the cell, cytoskeletal molecular motors transport and remodel membrane-bound cargos along microtubule and actin filament tracks. Typically, there are multiple actin and microtubule motors attached to the same cargo, which must coordinate to navigate a complex cytoskeletal environment and …
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Design and utilization of chiral selectors for enantioselective membrane transport
… of a selector for use in hollow-fiber membrane systems. Several chromatographically developed selectors show promise for large scale separation of enantiomers using hollow-fiber membrane technology. Chiral selectors derived from N-(1-naphthyl)leucine have been used in a hollow-fiber …
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Computational study of the structure and function of membrane transport proteins
Transport of the nutrients across the cell membrane is regulated by membrane transport proteins which selectively and efficiently transports materials across the membrane. In the present work I focus on the family of membrane transporters the so called sugar porters in both their mammalian and …
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Anions in hydrophobic environments: liquid-liquid extraction of sulfate and chloride, and membrane transport of chloride
The transport of an anion across a lipid bilayer or the extraction of an anion into organic solution requires the stabilization of a charged species in a hydrophobic environment. Due to the similar energetic barriers of both processes, liquid-liquid extraction can potentially be used as a model for …
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Towards functional assignment of Plasmodium membrane transport proteins: an experimental genetics study on four diverse proteins
Membrane transport proteins (MTPs) transfer nutrients, metabolic products and inorganic ions across membranes. Many MTPs are essential for Plasmodium blood infection and gain importance as candidate drug targets in malaria therapy, whereas the physiological functions of many MTPs still remain …
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Towards functional assignment of Plasmodium membrane transport proteins: an experimental genetics study on four diverse proteins
Membrane transport proteins (MTPs) transfer nutrients, metabolic products and inorganic ions across membranes. Many MTPs are essential for Plasmodium blood infection and gain importance as candidate drug targets in malaria therapy, whereas the physiological functions of many MTPs still remain …
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Separation of alkali metal cations and alkaline earth cations using ionizable crown ethers
… the separation of metal ions by extraction and membrane transport processes. A series of novel crown ether carboxylic acids , crown ether phosphonic acid monoesters, and crown ether phosphonic acids which possess lipophilic pendant groups were employed for the study of extraction and membrane …
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Enhanced transport through confined channels by stationary and fluctuating potentials
Binding-sites which facilitate the transport of substrates across membranes are ubiquitous in membrane proteins. To understand this fundamental process in cells, we build up a synthetic membrane system consisting of microfluidic channels and colloidal particles. Holographic optical tweezers are …
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A mathematical model of the airway epithelium: Computational studies of ion and water balance
… to investigate the time course of ion and water transport across airway epithelia. Model variables were intracellular and apical concentrations of sodium, potassium, chloride; apical, basolateral, and transepithelial membrane potentials; cell and apical volumes. Membrane transport processes …
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Biochemical characterization of nitrate transport at the plasma membrane of plant cells using isolated vesicles
… anion was used as a tracer for nitrate in membrane transport studies with isolated plasma membrane vesicles.
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IN VITRO ΚΑΙ IN VIVO ΜΕΛΕΤΕΣ ΓΙΑ ΤΗΝ ΕΚΤΙΜΗΣΗ ΤΗΣ ΒΙΟΔΙΑΘΕΣΙΜΟΤΗΤΑΣ ΜΕ ΒΑΣΗ ΦΥΣΙΚΟΧΗΜΙΚΑ ΧΑΡΑΚΤΗΡΙΣΤΙΚΑ ΤΩΝ ΦΑΡΜΑΚΩΝ ΚΑΙ ΤΩΝ ΦΑΡΜΑΚΟΤΕΧΝΙΚΩΝ ΜΟΡΦΩΝ
… HAS BEEN SUGGESTED. (B) IN VITRO AND IN VIVO MEMBRANE TRANSPORT STUDIES, FOR FIVE DRUGS, HAVE BEEN PERFORMED IN THREE DIFFERENT SYSTEMS. USING THE ESTIMATED RATE PARAMETERS, A NONLINEAR FITTING TO A THEORETICAL EQUATION HAS BEEN ATTEMPTED, IN ORDER TO EVALUATE THE ABILITY OF A SYSTEM TO …
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Characterization of FhuA 104/149C: a Double Cysteine FhuA Mutant with Normal Binding and Diminished Transport
… cells actively uptake these complexes via outer membrane-transport proteins such as FhuA in <em>Escherichia coli</em>. Structural analysis of receptors revealed a conserved β-barrel occluded by an N-terminal plug domain. The cell membrane TonB/ExbB/ExbD complex presumably supplies energy via …
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Controlled loading of cryoprotectants (CPAS) with cell volume constraints
… depends on knowing the permeability of the cell membrane to water and cryoprotective agents. Due to the large size of oocytes that requires microscopy methods which could be difficult to implement, micro fluidic device is presented in this study based on Coulter-principle to simultaneously …
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Macroscopic graphene membranes with tunable nanopores for highly selective mass separation
Membrane-based filtration enables energy-efficient separations of solutes, solvents, or gases, benefiting a wide range of applications including water desalination, nanofiltration, hemodialysis, solvent-based separation, or natural gas purification. Semipermeable polymeric desalination membranes …
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Sideroflexins enable mitochondrial transport of polar neutral amino acids
… of metabolism necessitates regulated transport of metabolites across the inner mitochondrial membrane. While many proteins enabling mitochondrial membrane transport of metabolites are known, how some metabolites are transported is not known, and several mitochondrial amino acid …
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