Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 98 for “"membrane integrity"”.
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Maintenance of fetal membrane integrity by cyclic cellular transitions during gestation and parturition
Fetal membranes line the intra-uterine cavity and perform protective functions during pregnancy. Rupture of membranes before term is deemed ‘catastrophic’ and contributes to infection, preterm birth, and neonatal death. During gestation, membranes repair and remodel through a balanced …
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Quantifying uncertainty in pathogen removal, membrane integrity monitoring and health consequences in the treatment of drinking water
… of oocysts of Cryptosporidium and viruses in membranes used to treat drinking water. In chapter 2, we examined variability and uncertainty in the determination of parameters used in pressure-based direct integrity tests of hollow fiber micro- and ultra-filtration membranes. We found that …
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Pengaruh pemberian ekstrak etanol jintan hitam (Nigella sativa) terhadap integritas membran spermatozoa dan kadar malondialdehyde (MDA) epididimis mencit yang dipapar timbal (Pb) esetat peroral
… cumin on levels of malondialdehyde (MDA) and membrane integrity of spermatozoa in the epididymis of mice were exposed to lead acetate orally. This study is an experimental study using completely randomized design (CRD) with 5 replications. Experimental animals used were mice strain Balb / c …
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Cryopreservation of Domestic Cat Epididymal Spermatozoa
… among any of the treatments when measuring membrane integrity or acrosomal status. There was significant difference when comparing the pre-cool motility value between the control and the human sperm preservation medium extender (HSPM), but this difference was not detected in either of the …
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An Investigation of Cytochrome Bd Quinol Oxidases of Vibrio Cholerae, Rhodobacter Sphaeroides, and Salmonella Typhimurium
… assay that can be used to study bacterial membrane polarization. This assay is a specific, rapid, and efficient method to screening potential ionophores and antibiotics. Chapter six utilizes the assay to investigate the mechanism of triclosan, a widely used bactericide. It was found that …
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AN INVESTIGATION OP POSSIBLE IN VITRO METHODS FOR STUDYING EYE IRRITANCY POTENTIAL
… procedures, namely the measurement of cell membrane integrity using fluorescein diacetate and ethidium bromide, and the quantitation of the release and activity of a cell membrane-bound enzyme, alkaline phospha1ase,were used to assess the qytotoxicity of a range of cationic, anionic and …
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Development of imaging techniques to assess tumour cell death
… fumarase to produce malate. With loss of plasma membrane integrity in dying cells fumarate can rapidly gain access to the enzyme. By measuring increased malate production in treated tumours after fumarate injection, cell necrosis can be assessed. It could be established that ²H MRS and MRSI …
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The use of aminoglycoside antibiotic therapy in neutropaenic patients with haematological disease
… of protein synthesis and disruption of cell membrane integrity. Principal use is in treatment of Gram negative infection although aminoglycosides have activity against some Gram positive organisms including staphylococci. Aminoglycosides are inactive against anaerobes. Acquired resistance is …
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The role of spectrin in Drosophila photoreceptor development.
… protein that interacts with the plasma membrane, forming a scaffolding and playing an important role in maintenance of plasma membrane integrity and cytoskeletal structure. In Drosophila, spectrin is composed of 3 subunits: α-spectrin, β-spectrin, and βH-spectrin. The interaction between …
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Influence of lipid antioxidants on soybean seed storage life
… Peroxidation of lipids, with resultant loss of membrane integrity, is theorized to be a primary event in seed aging. Lipid antioxidants might have the potential to protect dry seed by neutralizing free radicals, which propagate lipid peroxidation and other destructive events. Seed were treated …
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The effect of interval between inseminations and semen handling on in-vivo and in-vitro fertility of frozen-thawed boar sperm
… Samples (n = 20) were evaluated for motility and membrane integrity at the time of thawing and at 2, 6, 12 and 24 h intervals after thawing. Results indicated FTS can be diluted and stored at 17 or 26 °C for up to 2 h with no significant decrease in motility and membrane integrity (P > 0.10). …
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Nanosecond Pulsed Electric Field Effects on Cell Cycle and Apoptosis
… phenotype characterized by maintenance of membrane integrity, cell shrinkage, phosphatidylserine (PS) externalization at the plasma membrane, caspase protease activation, DNA fragmentation, release of cytochrome c from the mitochondrion, and membrane blebbing. An important regulatory …
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Cholesterol-Dependent Cytolysins and Perforin: Similar Pore-Forming Mechanisms in Pathogenic Attack and Human Immune Defense
… in bacterial infection pathway at the membrane level. Great interest in this family is due to their similarity, in structure and in pore-forming mechanism, with some human immune system proteins (MACPF). We focused our attention particularly on two bacterial CDCs, Perfringolysin O and …
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Function of abscisic acid in maintenance of maize primary root growth under water deficit
… in ROS levels preceded and caused loss of plasma membrane integrity in vp14 roots under water deficits. The results provide conclusive evidence that the maintenance of elongation in the maize primary root requires the accumulation of ABA both to restrict ethylene synthesis and to prevent excess …
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The “Apparent” Diffusion Coefficient of Electrons Through a Nafion Membrane
… and the durability of the proton exchange membrane (PEM). The PEM is not only used as the electrolyte for the cell but also as a physical barrier between the anode and the cathode. The integrity of this membrane is crucial to the functioning of the fuel cell. This thesis will examine using …
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Neuroprotection of AG490 in Oxidative Stress-induced Neuronal Death
… intracellular molecules, the destabilization of membrane integrity, and the mitochondrial dysfunction. In present study, we investigated whether AG490, a specific Janus kinases 2 (JAK2) inhibitor had an effect on oxidative stress-induced cytotoxicity in cultured primary cortical neurons. AG490 …
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Study of cell-cell communication using 3D living cell microarrays
… both prokaryotic and eukaryotic cells for membrane integrity and metabolic activity. To demonstrate the utility of this system, I have looked at a model "quorum sensing" system in Vibrio Fischeri, which operates by the emission and detection of a small chemical signal, an acyl-homoserine …
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Characterization and sequence variation of the virulence-associated proteins of different tissue culture isolates of African Horsesickness virus serotype 4
… Vero cells and investigate their cytotoxic and membrane permeabilization properties within these cells. The NS3 and VP5 genes of AHSV-4(1) and AHSV-4(13) were successfully inserted into a mammalian expression vector and transiently expressed in Vero cells. The transfection procedure was …
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Relationships between in vivo and in vitro heterospermic ranking, embryo development, and sperm characteristics of Holstein and Jersey bulls
… analysis of DNA fragmentation, acrosome integrity, plasma membrane integrity and disorder, and intracellular Ca2+), or standardized to equal numbers of motile sperm and recombined 1:1 resulting in the 9 H/J pairings for heterospermic IVF (H-VITRO-2). A competitive index (CI) was …
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Investigating the protein targets of the neuroprotective E3 ligase, CHIP
… proteins that are required for membrane repair and maintenance of membrane homeostasis. Given these functions, several types of membrane damage assays were conducted and suggested that CHIP KO cells are more sensitive to damage, despite retaining the ability to repair. This …
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