Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 11 of 11 for “"membrane charge"”.
-
Role of Bacterial Effectors SopD and SopB in Pathogenicity of Salmonella enterica serovar Typhimurium.
… remained elusive. Here I show that SopD affects membrane dynamics during S. Typhimurium invasion of epithelial cells. SopD promotes membrane sealing and macropinosome formation, events that may have important consequences for efficiency of bacterial cell entry in vivo. Furthermore, we demonstrate …
-
Analysis of charged polymer effects on recombinant retrovirus-mediated gene transfer success
… of retrovirus transduction modulation by these charged polymers, and it was found that they were capable of increasing or decreasing the flux of virus particles onto the cell surface. These effects, and adsorption in general, were independent of the cellular receptor-virus envelope interaction …
-
Caratterizzazione di membrane da nanofiltrazione
Nanofiltration (NF) is a pressure-driven membrane process, intermediate between reverse osmosis and ultrafiltration. Commercially available polymeric membranes have been used in a wide range of applications, such as drinking, process industry and waste water treatment. For all the applications …
-
Modeling nanofiltration for large scale desalination applications
… one to adjust and investigate effects of membrane charge, pore radius, and other membrane characteristics. The study shows how operating conditions such as feed flow rate and pressure affect the recovery ratio and solute rejection across the membrane. A comparison is made between the …
-
Structural transitions in self-assembled lipid systems driven by induced curvature: from cell-penetrating peptides to programmable vesicles
… peptides capable of traversing the plasma membranes of eukaryotic cells. While successful intracellular delivery of many biologically active macromolecules has been accomplished using these peptides, their mechanisms of cell entry are still under investigation. Ionic interactions between …
-
A Physicochemical and Biophysical Investigation into the Role of Lysyl- Phosphatidylglycerol in the Membrane of Staphylococcus aureus under mild acidic conditions
… lysyl-phosphatidylglycerol (L-PG) in its plasma membrane. The precise mechanisms by which L-PG facilitates tolerance to acidity and CAMPs remain under-investigated, due to the lipid’s lability in mild aqueous conditions. This study examines the role of L-PG in responses to epithelial defences and …
-
Self -Assembly Between Biomacromolecules and Lipids
… (002) polar planes parallel to the negatively charged sugar-phosphate DNA backbone, which indicates that molecular details of the DNA molecule are imprinted onto the inorganic crystal structure. The resultant nanorods have (002) planes tilted by ∼60° with respect to the rod axis, in …
-
EXPLORING THE EFFECTS OF PHYSIOLOGICAL ENVIRONMENT ON AMYLOID AGGREGATION
… schemes in the presence of phospholipid membranes, solvated glucose molecules and added trailing sequences. Phospholipid membranes, composed of a heterogeneous distribution of lipid molecules, serve as packaging envelopes in cellular systems. But several studies have suggested a role of …
-
Modeling low-pressure nanofiltration membranes and hollow fiber modules for softening and pretreatment in seawater reverse osmosis
… of low-pressure nanofiltration (NF) hollow fiber membranes, particularly suited for water softening and desalination pretreatment have lately been fabricated in-house using layer-by-layer (LbL) deposition with chemical crosslinking. These membranes can operate at exceedingly low pressures (2 bar), …
-
Characterisation of a harvesting step for monoclonal antibodies from mammalian cell culture
… unpredictably and the ability of the positively charged filters to adsorb DNA from process material was unknown. To direct the development of an assay to quantify the ability of depth filters to adsorb DNA, the molecular weight of DNA from a large-scale, fed-batch, mammalian cell culture vessel …
-
Structural study of lipid bicontinuous cubic phases for cellular delivery
… area per volume, and highly ordered pore and membrane network. As the building block of the cubic phases is lipid bilayer, it is also possible to incorporate both hydrophilic and hydrophobic molecules of interest in the bulk cubic phase system. The structural characteristics of bicontinuous …