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Showing 1 to 12 of 12 for “"membrane biogenesis"”.
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Untersuchungen zur Funktion von Alb 3 im plastidären Proteintransport von Arabidopsis thaliana
… the integration of proteins in their respective membranes. To the date, homologs within mitochondria (Oxa1p), E. coli (YidC) and chloroplasts (Alb3) have been investigated. Alb3 is the least investigated protein of this triple. A function within thylakoid membrane biogenesis is discussed for …
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RalGDS-Dependent Cardiomyocyte Autophagy Is Necessary for Load-Induced Ventricular Hypertrophy
… common feature of cell growth and autophagy is membrane biogenesis and processing. The exocyst, an octomeric protein complex involved in vesicle trafficking, is implicated in numerous cellular processes, yet its role in cardiomyocyte plasticity is unknown. Here, I set out to explore the role of …
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With No Gly-Loop Family of Kinases
… The PV is filled with a network of tubulated membranes, which are thought to facilitate trafficking of effectors and nutrients. Despite being critical to parasite virulence, there is scant mechanistic understanding of the network's functions. Phosphoproteomics data indicated that many PV …
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ATG8 Regulation and Function in Non-Canonical Autophagy
… (LC3s and GABARAPs) are recruited to double membrane autophagosomes where they facilitate substrate capture, membrane biogenesis and maturation. LC3 proteins can also be recruited to single membrane, endolysosomal compartments through a distinct pathway known as “non-canonical autophagy”, …
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Membrane Systems in Cyanobacteria
… prokaryotes with three highly differentiated membrane systems: plasma membrane, outer membrane, and an internal system of thylakoid membranes. The presence of different membrane systems lends these cells a unique complexity among bacteria. Many details concerning the interrelations between the …
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Characterization And Identification Of Novel Regulators Of The Synthesis Of Phospholipids
… are the most abundant lipids in cell membranes. The synthesis of phospholipids is crucial for cellular membrane biogenesis and nearly all aspects of cellular processes. Understanding the regulation of synthesis of phospholipids is beneficial to our fundamental knowledge of cell biology …
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The Physiological Effects of CD38 in Prostate Cancer: A multifunctional NAD'ase capable of regulating cell metabolism, gene expression, and therapeutic response
… increased macromolecule biosynthesis, sustain membrane biogenesis, and cell survival. Nicotinamide adenine dinucleotide (NAD+) is linked all aspects of cell metabolism though its ability to act as both an oxidizing and reducing agent for hydride transfer reactions. Proper regulation of NAD+ is …
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Exploration of Cell Cycle-Specific Essential Gene Functions in the Microbial Plant Chlamydomonas Reinhardtii
… including transcription, translation, and membrane biogenesis. The other class exhibited wild-type cell growth rate, and entered the S/M program on time; mutant cells then developed various S/M-specific defects. This class included genes directly involved in DNA replication and chromosome …
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Structural and Mechanistic Roles of Novel Chemical Ligands on Quorum Sensing Transcription Regulator SdiA in Enterohemorrhagic Escherichia coli
… sources, signaling molecules, and substrates for membrane biogenesis. While exogenous AHL renders SdiA much higher stability and DNA binding affinity, we propose that OCL may function as a chemical chaperone placeholder in the absence of AHL and stabilizes SdiA as a dimer, allowing for some basal …
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A role for a predicted E. coli inner membrane lipoprotein in cell envelope integrity
… coli</em> is the possession of a double-membraned cell envelope. The outer membrane provides an additional layer of protection against hydrophobic molecules including antibiotics, contributing to the multidrug resistance crisis. The Gram-negative membrane is composed of phospholipids, …
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The Regulation of the Phosphatidate Phosphatase Gene <em>PAH1</em> and Its Regulatory Role on Cell Homeostasis
… also acts as an important regulator of nuclear membrane biogenesis, the transcriptional regulation of many inositol-sensitive upstream activating sequence (UAS<em><sub>INO</sub></em>)<em></em>containing genes needed for phospholipid synthesis, vacuole homeostasis, and lipid droplet formation. …
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Role of VimA in Cell Surface Biogenesis in Porphyromonas gingivalis
… shown to play a significant role in the biogenesis of gingipains (trypsin-like cysteine proteases). The <em>vimA </em>has also been demonstrated to play a role in hemolysis, hemagglutination, autoaggregation, posttranslational protein modification, and LPS biogenesis. Though significant …