Global ETD Search
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Showing 1 to 7 of 7 for “"melting curves"”.
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Optimization of force fields for molecular dynamics
… the potential parameters while the slope of the melting curve is not. The sensitivity variations make it difficult to satisfy both observations simultaneously. We conjecture that there is no set of parameters that reproduces experimental melting curves of short peptides that are modeled with the …
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PNA-Ligand Bioconjugates as Potential Building Blocks for Sequence-Specific, Metal-Mediated DNA-/RNA-Cleavage
… DNA hybridization behaviour was examined by UV melting experiments, revealing the intercalating effect of a terminal terpyridine ligand. A new criterion for the significance of PNA DNA melting curves was introduced. The influence of the replacement of one internal PNA monomer with two …
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Brillouin studies of diopside and H2O
… properties of H2O. We determined the melting curve of Ice VII by simultaneous measurements of sound velocity and angle-dispersive synchrotron x-ray diffraction in a membrane-type diamond anvil cell with resistance heating at elevated temperatures to 873 K at pressures of 2 GPa to 14 …
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X-ray diffraction study of compressed solid argon and krypton
… very precise x-ray lattice parameters along the melting curves of solid argon and solid krypton and to measure changes in vacancy concentrations along quasi-isochores for both these substances. The uncertainty of the lattice parameters obtained along melting was estimated to be 27 ppm. These …
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Investigation of the determinants of thermal stability of the nitrile hydratase from Geobacillus pallidus RAPc8
… further study. Using activity assays and protein melting curves, their individual thermal stability contributions were determined and represented as the difference in free energy of thermal unfolding (change in Gibbs free energy) of the single and composite mutants relative to the wild type …
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Quantitative impurities effects on temperatures of tin and aluminium fixed-point cells
… The experimental undoped liquid-solid transition curves were also compared against theoretical curves (calculated from atheoretical model MTDATA). The results obtained did not disagree with the Hansen interpolated values (though there was considerable uncertainty in some of the measurements (e.g. …
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Potential prebiotic roles of (amino-)acylation in the synthesis and function of RNA
… sites of 2'-O-acetylation were assessed by UV melting curve analysis. Remarkably, the acetyl groups caused a consistent decrease in Tm of between 3.0-3.2 °C. Thermodynamic parameters indicated a decrease in duplex stability that was consistent with a decrease in hydration of the minor groove …