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Showing 1 to 3 of 3 for “"melanocyte stem cells"”.
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The Establishment and Regulation of Melanocyte Stem Cells in Zebrafish
<p>Stem cells are the cells that regulate the growth and repair of tissues in adult organisms. In this thesis, I sought to develop methodologies to dissect the function and regulation of stem cells during zebrafish melanocyte regeneration.</p><p>In the first part of this thesis, I develop a drug …
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Coordinating Stem Cell Behavior in the Hair Follicle
<p>Tissue stem cells perform important functions throughout an organism's life. They generate new cells to replenish cells that are lost during normal wear and tear or in response to acute injury. Remarkably, hair follicles naturally undergo repetitive cycles of regeneration and degeneration, a …
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Not Black and White: BMP Signaling Drives Melanocyte Differentiation Downstream of Stem Cell Activation
<p>Tissue stem cells (SCs) maintain, regenerate, and repair the body over the course of an organism's lifetime. To preserve their long-term function, SCs must exert precise control over their cell state dynamics as they move from quiescence to activation and commit to full differentiation. My …