Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"medicinal applications"”.
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Fluorinated Organic Molecules for Medicinal Applications
<p>The significant applications of fluorinated molecules in the pharmaceutical, agrochemical, and material sciences make them attractive synthetic targets. Difluoromethylation methods are of exceptional value and a limited number of techniques are available to perform that transformation. The …
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Structural studies of phosphinegold(I) thiolates with potential medicinal applications / by Douglas Robert Smyth.
Reports the preparation of mononuclear triorganphosphinegold(I) mercaptobenzoic acids, where x = 2,3 or 4, R = alkyl or aryl, and Y is a bridging alkyl or ferrocene group. Demonstrates that the solid state chemistry of phosphinegold(I) thiolates remains difficult to predict when competing intra- …
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Neuro-electronic technology in medicine and beyond
… The final sections consider a future for non-medicinal applications of neuro-electronic technology. Social attitudes towards use for both medicinal and non-medicinal purposes are discussed, and the viability of use in the latter case assessed.
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Antibiotic Potential of Hericium and Hohenbuehelia Species
… are fungal genera of interest for their medicinal applications and production of a variety of secondary metabolites. Erinacine A, produced by Hericium species, and pleurotin, produced by Hohenbuehelia species, are sought after for neuroregenerative effects and anti-cancer prospects, …
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PHARMACOKINETICS AND ORAL DELIVERY OF POLYMETHOXYLATED FLAVONES
… reported extensively. To further evaluate the medicinal potentials of three polymethylated flavones, namely tangeretin (TAN), apigenin trimethyl ether (ATE), and luteolin tetramethyl ether (LTE), their pharmacokinetic profiles were assessed in Sprague-Dawley rats. Aqueous solubility has been …
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The synthesis of amphiphilic diblock copolymers: An investigation into the formation of micelles as a function of hydrophobic block length
… of molecular weight for eventual use in medicinal applications. Based on previous findings of copolymers with low weight hydrophobic blocks failing to micellize, it was hypothesized that increasing the poly(methyl acrylate) block length would allow for micelle formation. 1H-NMR …
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Development of an RNA aptamer to PD173955N through SELEX
… which makes them less desirable for medical applications.;Aptamers are newly developed reagents and their utilization in medicinal applications is so far very limited. However their characteristics make them perfect tools to help solve problems associated with PD173955. Here we report a …
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Palladium-catalyzed C-N cross-coupling reactions toward the synthesis of drug-like molecules
… because of many academic and industrial applications. This work will focus particularly on palladium-catalyzed cross-couplings of amine-containing compounds with aryl halides. The scope of the BrettPhos precatalyst for the cross-coupling of ortho-substituted aryl iodides with amides is …
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Transcriptomic analysis of the response of the lactic acid bacteria Lactococcus piscium for the identification of possible adaptive genes during thermal shock in cold and warm temperatures
… a versatile role in research, food, farming and medicinal applications, but also play a role as a source of food spoilage. The effects of temperature changes has yet to be studied in depth. In this study, to analyze in a transcriptome level, cold and heat shock stress to spoilage lactic acid …
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Comparison of dose-dependent outcomes in induction of cytogenotoxic responses by novel glucosyl flavonoids
… for improved incorporation in food and medicinal applications. Quercetin and its glucosides are known to induce genetic instability and decrease cell proliferation, which are possible mechanisms of anti-carcinogenesis in in vitro and animal studies. Using an in vitro system of Chinese …
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Fungi associated with the die-back of Pterocarpus angolensis (kiaat) in South Africa
… tree is commercially used in several traditional medicinal applications and is well-known as a source of timber for woodcarving and furniture. A single serious disease known as mukwa has been reported on P. angolensis, and the cause has been attributed to the generalist fungus Fusarium oxysporum. …
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Stress relief: Exercising Lewis acid catalysis for donor-acceptor cyclopropane ring-opening annulations, a basis for new reaction methodologies
… their functions in biology and potential for medicinal applications. Although bioactive natural products demonstrate medicinal promise, poor pharmacological effects require further derivatization because semisynthesis is not sufficient to refine adverse pharmacokinetics. For some active …
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Functional characterization and analysis of Carica papaya SHORT VEGETATIVE PHASE (CpSVP)
… is known for its nutritional benefits and medicinal applications. Sex in papaya is controlled by a pair of nascent sex chromosomes with two slightly different Y chromosomes that distinguish males (XY) and hermaphrodites (XYh). These two Y chromosomes diverged about 4,000 years ago with only …
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Polystyrene coated iron-platinum drug delivery platforms for theranostics
… of being used in both therapeutic and diagnostic applications.2,3 nanoparticles have been shown to passively accumulate in tumors, making them useful materials for developments in cancer research.4 Iron-platinum (FePt) nanoparticles have an excellent potential as delivery agents for medicinal …
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Profiling studies of five Namibian indigenous seed oils obtained using three different extraction methods
… a great variety is used for food, cosmetics and medicinal applications. Seed oil production from indigenous sources has economic importance for Namibia and is an asset for improving the livelihoods of local communities. Knowledge of the quality and composition of these oils can be used towards …