Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 94 for “"medical diagnostics"”.
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Hydrogel-based microfluidic assays for multiplexed medical diagnostics
There is high demand for next-generation biomolecule detection platforms arising from clinical need for more robust point-of-care diagnosis systems, fundamental research need to characterize complex biological processes, and the emergence of personalized medicine. These detection systems should …
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Design and Development of a Portable Microfluidic System for Medical Diagnostics
… the development of a portable LOC system for medical diagnostics. A modular microfluidic LOC architecture is presented along with its implementation in two successive generations of devices. The architecture allows for rapid prototyping and simple design changes at low cost. Next, the design, …
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Development of thermostable affinity reagents for low-cost, paper-based medical diagnostics
… the development of robust point-of-care (POC) diagnostics, which provide accurate results and can be employed by users with minimal medical training and limited access to basic infrastructure. One of the most common POC diagnostic formats is the immunochromatographic rapid diagnostic test, …
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Polymer fabrication and microfluidic unit operations for medical diagnostics on a rotating disk
Die vorliegende Arbeit ist motiviert durch den in der medizinischen Diagnostik <br>anhaltenden Trend hin zu dezentralen, patientennahen Untersuchungen (Point of <br>Care) und dem Potential der Mikrofluidik, diesen Trend zu unterstützen. Ziel der <br>Arbeit ist die Entwicklung einer zentrifugalen …
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Advanced analytical strategies to determine biomedical parameters for medical diagnostics, drug delivery, and therapy
<p>"Biomedical parameters are critical for diseases prognosis, diagnosis and therapy. Many research groups have dedicated their studies to develop analytical instrumentation and apply analytical methods to determine biomedical parameters that have the potential to help with disease control and …
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Development of a sampling system for the collection of exhaled breath condensates and its subsequent analysis using 2-dimensional gas chromatography
… as extensively as blood or urine samples for medical diagnostics. Some of the major reasons for this include the lack of a standard method of sample collection, control of variability, reliable detection at trace level and quantification. Breath analysis has recently attracted renewed interest …
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Chemical and biological sensors based on organic semiconductors
… resonance biosensors for biotechnology and medical diagnostics applications. During completion of my research projects I designed and optimized several device architectures using numerical simulations and fundamental physical evaluation of sensing mechanism and performance. Fabricated …
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Self-supervised multi-contrast MRI denoising
Magnetic Resonance Imaging (MRI) is pivotal in medical diagnostics, offering essential multi-contrast imaging capabilities. However, MRI quality is often compromised by inherent noise, which can hinder both image clarity and analytical accuracy. This thesis presents the "Corruption2Self" (C2S) …
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Biologically inspired computational neural models for motivated behavior, learning, and memory
… from computer vision to language processing and medical diagnostics. While the majority of AI applications involve data classification, detection, and predictive modeling, fewer studies have explored the creation of motivated autonomous agents. The integration of neurobiological principles into …
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Development of adhesive bonding and functional testing systems for in-process inspection of hot embossed microfluidic devices
… with a wide-variety of applications such as medical diagnostics, drug development, and DNA analysis. The transition of microfluidic devices from research to industry has stimulated interest in producing them at low costs and high volumes. Hot embossing has been of interest lately as a …
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Microfluidic approaches to the synthesis of complex polymeric particles
… objective. Varied applications including medical diagnostics. designer fabrics and optical devices could benefit from the availability of geometrically complex and chemically inhomogeneous particles. Microfluidics has recently emerged as an important alternative route to the synthesis of …
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Dynamic complex smart colloids for the detection of biomolecules
… beverage industry, environmental monitoring and medical diagnostics. In Chapter 2, we demonstrate an example of using emulsion agglutination assay for E.coli sensing with a continuous phase carbohydrate surfactant. In Chapter 3, we expand the emulsion assay by using interfacial bioconjugation …
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Volumetric Optical Imaging of Tissue Microstructure for Grading of Dysplasia In Vivo
Optical imaging offers unique advantages in medical diagnostics. In particular, high resolution, fast imaging speed, and strong depth penetration make optical coherence tomography (OCT) an attractive modality for non-perturbatively investigating structural changes in tissue that accompany disease …
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Improving Computational Efficiency of MRI Brain Tumour Analysis Using Hybrid Machine Learning Models
Brain tumor is a critical challenge in medical diagnostics, worsen by the high mortality rate and prevalence worldwide of the disease. Accurate and early detection is paramount to improving patient outcomes. This study focuses on evaluating the usefulness of machine learning (ML) and deep learning …
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An Experimental re-evaluation of Photon Mass Attenuation Coefficients
… in several disciplines. They are of value for medical diagnostics, radiation therapy, material science, etc. Currently, photon mass attenuation coefficients derived from model calculations are widely used. This project directly measured the photon mass attenuation coefficients of water and a …
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Multi-parametric photoacoustic/ultrasound localization (PAUL) imaging and its applications
Noninvasive biomedical imaging technologies play a critical role in medical diagnostics, yet each modality has inherent limitations in spatial resolution, functional sensitivity, or molecular specificity. Hybrid imaging approaches have been developed to address these limitations, providing …
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AI-assisted Development of Energy Harvesters for POCT
… pathogen detection and energy harvesting in biomedical applications. The work is centered on the design and validation of impedance spectroscopy-based biosensors that offer sensitive, and specific pathogen detection, crucial for timely healthcare interventions. A key component of this research …
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Exploring the lifecycle of artificial intelligence – deep learning for 1D to 4D biomedical data
… Intelligence - Deep Learning for 1D to 4D Biomedical Data" presents a comprehensive exploration of the Artificial Intelligence (AI) lifecycle as applied to various domains within the life sciences and medicine, specifically focusing on the application of Machine Learning (ML) and Deep Learning …
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Utilization of TMV-TEMPO as an in Vivo MRI Sensor of ROS Production in Liver Inflammation and as a DNP Agent
… images of soft tissues in living subjects for medical diagnostics. This PhD dissertation details the i) utility of a nitroxyl-modified tobacco mosaic virus (TMV) as an in vivo MRI contrast agent for detection of reactive oxygen species (ROS) in murine model of liver inflammation and ii) its …
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Computational design for the next manufacturing revolution
… of metal parts in the aerospace, automotive, and medical industries. Whole-garment knitting machines allow automated production of complex apparel and shoes. Manufacturing electronics on flexible substrates makes it possible to build a whole new range of products for consumer electronics and …
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