Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 88 for “"mechanical force"”.
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Development of a Generalizable Assay for Probing the Effects of Mechanical Force on the Function of Fluorescent Proteins within Molecular Tension Sensors
… behavior, providing both biochemical factors and mechanical signals to influence the form and function of cells. The process by which cells sense and respond to environmental mechanical signals is often mediated through force-dependent changes in protein structure and function through a poorly …
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Investigation and characterization of a high energy piezoelectric pulse
… materials. The high energy PPG converts mechanical energy into electrical energy, storing that energy in its internal capacitance. The energy storage of the high energy PPG developed here is more than an order of magnitude greater compared to previous investigations [1-2]. The large …
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Morphogenetic forces planar polarize LGN/Pins in the embryonic head during Drosophila gastrulation
… to the proper development of epithelia. How forces are transmitted across the developing embryo and how these forces along with genetic programs that are active at this time contribute to coordinated cell behaviors remains a long-standing question in biology. This work addresses how forces …
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The Electrical Stimulation of Bone Formation.
… electric current and potential in response to mechanical forces. The same phenomena were reported in 1962 by Bassett who found that the potentials developed in the area of compression were negative, and positive in the area of tension. In 1968 Cochran performed experiments on wet bone as well …
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Mechanophore activation at heterointerface and surface crowdedness as a determining factor
"When bringing ""mechanical force"" and ""polymer"" into conversation, one might naturally relate to everyday scenarios such as worn cloth, broken taillight and cracked paint. The intuitive viewpoint reflects the historic consensus that mechanically induced chemical changes are destructive. …
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Force-induced mechanochemical reactions in polymeric systems
… the field of mechanochemistry, the energy from mechanical force is harnessed to induce and direct chemical reactions. One focus of the research presented investigates the spiropyran (SP) mechanophore (force-sensitive molecule) incorporated into different polymer systems. The SP mechanophore …
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Elimination of PZT thin film breakage caused by electric current arcing and intrinsic differential strains during poling
… more susceptible to breakage if any sort of mechanical force is present. It was determined that these stresses were caused by differential strains due to incomplete metal layer coverage. Second, the electrical arcing that is frequently taking place during poling sends a mechanical shock wave …
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Design and manufacturing analysis of resonantly coupled circuits and other components used for applied wireless power transmission : application analysis
… polymeric material to expand, thereby creating a mechanical force to disengage the locking mechanism. The analysis considers the force generated through wireless transmission, as well as the forces required to disengage the locking mechanism. The general physics of wireless energy transmission …
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Mechanically mediated trithiocarbonate addition to commodity polymers for a more circular economy
Mechanical recycling, while thought of as environmentally conscious, is not nearly as effective as it is lauded to be. Great levels of mechanical force cause chain-scission and lower product value while simultaneously only working once, maybe twice before the material is useless. Studies to harness …
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Experimental and theoretical investigation of mechanism of Kinesin motility
… chemical energy from ATP hydrolysis to generate mechanical force to power its progressive motility along a microtubule track. The mechanism of motility has been a subject of extensive study for last decade. Recently, it has been proposed that novel element-cover strand-is essential in …
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Melanin-independent accumulation of turgor pressure in appressoria of Phakopsora pachyrhizi
… fungi accumulate turgor pressure that produces a mechanical force enabling the direct penetration of hyphae through the epidermis. Melanin functions as an impermeable barrier to osmolytes, which allows appressoria to accumulate high turgor pressure. Deficiency of melanin in appressoria reduces …
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Towards reversible mechanochemically triggered strengthening, toughening and assembly of soft materials
… is on many levels inspired by biology, where mechanical force regulates the flux of ions through channels, triggers electrochemical impulses, and activates the rearrangement of protein complexes. A key attribute of many biochemical reactions is reversibility, as this enables the machinery of …
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Simulation of actin cytoskeleton structure and rheology
… In addition, it's generally known that mechanical force plays an important role in the physiology of eukaryote cells whose major structural component in cortex is actin cytoskeleton. Thus, understanding the origin of viscoelasticity of cross-linked networks should be crucial to figure …
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Spiropyrans as color-generating mechanophores
… tunneling microscopes or single molecule force experiments using atomic force microscopy or optical tweezers are recent developments. However, these methods are limited in their usefulness by the small number of molecules that can be affected at any one time. Combining these two concepts …
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Mechanical Signals for Compensatory Lung Growth Assessed by High Resolution Computed Tomography
… (HRCT) to understand the role of intra-thoracic mechanical force and its distribution in regenerative growth in dogs i.e. to quantify lobar lung volumes and density gradients in normal and post-pneumonectomy (following lung resection) lungs. HRCT was used to quantitatively assess regional …
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Electrospinning applications in mechanochemistry and multi-functional hydrogel materials
Mechanochemistry is the use of mechanical force to perform chemical reactions and has the potential to bring self-healing functionality to the molecular level. The mechanically induced reactions can become productive when stress-sensitive molecules, or mechanophores, are incorporated into …
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Mechanical Loading for Modifying Tissue Water Content and Optical Properties
… such as water and protein, and the mechanical and optical properties of human skin is important to understand its complex nature. Localized mechanical loading has been proven to alter optical properties of tissue, but the mechanisms by which it is accomplished have not been studied …
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Minimally invasive neuromodulation using mechanically-sensitive ion channels and magnetically-actuated nanotransducers
… approach of utilizing magnetic nanoparticles as mechanical force transducers to achieve minimally invasive, wireless neuromodulation using magnetic fields as the stimulation modality. By leveraging magnetic fields and mechanically sensitive ion channels, this method aims to provide precise …
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Computational modeling of protein-biomolecule interactions with application to mechanotransduction and antibody maturation
… we sought to characterize effects of applied mechanical force on protein structural and biochemical properties. Despite growing experimental evidence of force-regulated cell behavior, the molecular mechanisms involved in force sensing and transmission are still largely unknown. We adapted a …
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Venous materials towards interactive fluidic mechanism
… that allows users to design the geometry, input mechanical force, and simulate the flow results dynamically. Furthermore, this thesis presents the fabrication process that was developed for Venous Materials, which was documented and demonstrated in a hands-on workshop. Finally, this thesis will …
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