Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"mechanical ablation"”.
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Investigation of Advanced Cavitation Agents for Nanoparticle-Mediated Histotripsy (NMH) Applications
… ultrasound with engineered nanoparticles to mechanically ablate targeted tissue with cavitation. Unlike conventional histotripsy, which requires high negative pressures (>25 MPa) for treatment, NMH utilizes nanoparticles, which enable cavitation at significantly lower pressures (<15 MPa), …
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Al/Al2O3 microchannel plasma chemical reactor for ozone synthesis
… from aluminum foil by chemical processing and mechanical ablation with photolithographic steps. Channels with 3 cm in length and 250 μm in width at the aperture of the channel produce spatially-uniform glow discharges in O2 or dry air feedstock gases at a pressures of 1 atmosphere and flow …
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Ultrasonic Effervescence: Investigations of the Nucleation and Dynamics of Acoustic Cavitation for Histotripsy-Based Therapies
Histotripsy is a noninvasive mechanical ablation method that uses focused ultrasound to disintegrate target tissues into acellular homogenate through the generation of acoustic cavitation and is currently being developed for numerous clinical applications. Histotripsy uses high-pressure (>10 MPa), …
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Determining the Oncological and Immunological Effects of Histotripsy for Tumor Ablation
… non-invasive, non-thermal, image-guided cancer ablation modality that has recently been approved for its first clinical trial in the United States (NCT04573881). Histotripsy utilizes focused ultrasound to generate acoustic cavitation within a tumor to mechanically fractionate targeted tissues. …
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Mechanical High-Intensity Focused Ultrasound (Histotripsy) in Dogs with Spontaneously Occurring Soft Tissue Sarcomas
… ultrasound (HIFU) ablative technique that causes mechanical fragmentation of tissue, resulting in liquefied acellular debris with histologically clear demarcated boundaries between treated and non-treated tissues. The acellular debris may include tumor antigens with preserved immunogenicity and …