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Showing 1 to 6 of 6 for “"matrix tablets"”.
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Development of Co-processed Plasticized Cellulose Acetate for Sustained Release Matrix Tablets
… a good polymer candidate for sustained release matrix tablets. Sustained release matrix tablets of cellulose acetate can be prepared by direct compression or wet granulation methods. However, previous studies showed that a large amount of CA was required to achieve the desired sustained release …
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The use of roller compaction as granulation method for hydrophilic extended release matrix tablets
… (HPMC) based hydrophilic extended release matrix tablets. Roller compaction is a dry granulation method where powder material is fed through a hopper between two counter-rotating rolls and pressed into a ribbon like compact. The compact is thereafter milled to obtain granules. Two full …
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Inter-Grade and Inter-Batch Variability of Pharmaceutical-Grade Sodium Alginate
… on the functionality of sodium alginate used in matrix tablets was investigated with a focus on compression properties, swelling, erosion behavior of alginate matrix tablets, and drug release from matrix tablets. The compression behavior of four grades and three batches of sodium alginate were …
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Development of Sodium Benzoate Tablets with Dual Burst Release: Hydrophilic Matrix System
… dosing frequency. To achieve dual burst release, tablets with hydrophilic matrix system were developed. These tablets consist of a hydrophilic matrix system that incorporates the API. The hydrophilic polymers swell up and function as a barrier and control the release of the API. A total of 27 …
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Release adjustment of drug combinations with different drug solubility
… in drug for controlled release drug delivery as matrix tablet and multilayer pellet system. As tablet system, employing direct compression method, irrespective to type of polymers, release of propranolol HCl was much faster than carbamazepine due to solubility differences. The modified method of …
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DEVELOPMENT OF SUPERSATURATED MATRIX SYSTEMS FOR POORLY WATER-SOLUBLE COMPOUNDS BASED ON SPRAY-DRIED SOLID DISPERSIONS
… dispersion (ASD)-loaded controlled release (CR) matrix system for poorly water-soluble drug in order to enhance its solubility and dissolution rate while maintaining the stability of the supersaturated state during and after dissolution. Two types of polymeric carriers, namely hydroxypropyl …