Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"maternal proteins"”.
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Precise Temporal Regulation of Ribonucleoprotein Complexes during the Drosophila Maternal-to-Zygotic Transition
In early animal embryos, maternally loaded mRNAs and proteins regulate development prior to the handover of control to zygotically expressed gene products in a process known as the maternal-to-zygotic transition (MZT). RNA-binding proteins (RBPs) tightly regulate the translation, stability, and …
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C. Elegans OMA-1 and OMA-2 are Transcriptional and Translational Repressors of Germline Fate
… roles for two CCCH type RNA binding zinc finger proteins OMA-1 and OMA-2 during C. elegans germline development and early embryogenesis. Previously, OMA proteins were shown to be required for oocyte maturation but they were not assigned any molecular functions. My thesis demonstrates …
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CRISPR activation screening at single-cell transcriptomic resolution: discovering new regulators of zygotic genome activation
The maternal-to-zygotic transition in mammals consist of the passing of the developmental control from the mother to the embryo and involves two major events: the depletion of maternal products and the activation of the zygotic genome. Zygotic genome activation, or ZGA, coincides with dramatic …