Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 27 for “"maternal plasma"”.
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Maintenance of pregnancy in goats: Relationships between the fetus, the corpora lutea and the concentrations of progesterone in the maternal plasma
… progesterone was measured by radioimmunoassay of plasma samples collected frequently from the jugular vein from day 0 to day 75.
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Maternal Plasma and Corresponding Egg Yolk Hormone Variation within a Clutch and Across the Nesting Season of the Loggerhead Sea Turtle (Caretta Caretta)
In oviparous vertebrates, the maternal transfer of steroid hormones to egg yolk can vary among species, within and among clutches, seasonally, due to age, and in response to social and environmental cues. In previous studies, significant effects on hatchling phenotype, sex and survival have been …
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Administration of arginine does not alter material circulating concentration of C-type natriuretic peptide in pregnant sheep: A thesis submitted in partial fulfilment of the requirements for the Degree of Bachelor of Science with Honours
… that treatment with arginine would decrease plasma CNP concentration in ewes pregnant with triplets, but have no effect on singleton pregnancies. To test this, pregnant ewes carrying singles or triplets (about day 100 of gestation) received an i.v. bolus injection of either saline solution …
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Next Generation Sequencing nell'analisi del DNA fetale da plasma materno per la diagnosi prenatale non invasiva di malattie genetiche
… fetal mortality. The discovery of fetal DNA in maternal plasma had opened new opportunities for non invasive diagnosis and to date, cffDNA( cell-free fetal DNA) is considered the ideal target to conduct a noninvasive diagnosis (NIPD). Simultaneously, the large develop of next generation …
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Gene and Protein Profiling of the Preeclamptic Placenta
… was seen. Antibody microarray screening of maternal plasma showed that late and early onset PE as well as PE with notching and IUGR showed different inflammatory responses. Conclusions The changes in gene expression suggested that PE may be a three-stage disease with notch as a reversible …
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Pharmacokinetics of Bupropion and its Pharmacologically Active Metabolites in Pregnancy
… the formation of OHBUP; the latter is the main plasma metabolite of bupropion and is thought to contribute majorly to pharmacological efficacy of the drug. CYP2C19 enzyme is involved in hydroxylation of bupropion, as well as TB and EB. Pregnancy-associated changes in maternal physiology may …
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DEVELOPMENTAL CONSEQUENCES OF GESTATIONAL CANNABIS EXPOSURE IN RAT ACROSS THE LIFESPAN
… methods for THC and Cannabidiol (CBD). Maternal plasma levels of cannabinoids and metabolites were measured at gestational days (GD) 6 and 20 following exposure to High-THC or High-CBD smoke, or injected THC or CBD. The results showed that THC and CBD levels in maternal plasma were 20x …
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Maternal and Umbilical Plasma Lipids Obtained During Elective Cesarean Section as Predictors of Macrosomia in Diabetic Pregnancy
… diabetic pregnancy, macrosomia, umbilical plasma lipids, maternal plasma lipids.</p>
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The metabolism of cortisol in the human feto-placental unit
… binding, has been applied to umbilical cord and maternal plasma samples. In mixed cord plasma the mean cortisol concentration was 6.0 ± 0.8 µg/100 ml (n = 9) and the mean cortisone concentration was 13.5 ± 2.9 µg/100 ml (n = 9). In cord arterial plasma the mean cortisol concentration was 6.3 ± …
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Salmon in Pregnancy Study (SIPS): the effects of increased oily fish consumption on maternal nutrient intake, fatty acid status and immunity
… consumption during pregnancy will: a) increase maternal LC n-3 PUFA intake b) increase maternal LC n-3 PUFA status, c) alter maternal immunity, which may influence the developing foetal immune system in a way that would decrease atopy risk for the offspring. Pregnant women (n = 123) with high …
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CHARACTERIZATION OF PLACENTAL AUTOPHAGY AND BIOENERGETICS, AND MATERNAL MICRORNAS PROFILING IN OBESE PREGNANCIES AND GESTATIONAL DIABETES MELLITUS
BACKGROUND Maternal obesity (MO) is expanding worldwide, contributing to Gestational Diabetes Mellitus (GDM) prevalence. The altered placental function and intrauterine environment of MO and GDM are associated with adverse maternal and fetal outcomes, with short- and long-term complications. …
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Axis of placental ageing in adverse pregnancy outcomes
… and significantly adversely impacts both maternal and fetal outcomes. Intrauterine growth restriction (IUGR) is defined as the inability of the fetus to reach normal growth potential within the uterus as a result of various genetic, environmental, or placental factors. Premature ageing of …
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An assessment of the effects of dietary oil supplementation on fetal survival in gilts at 40 days of gestation
… and fatty acid concentration in gilt plasma and fetal head and body. Three diets contained 4% (w/w) added fat either as coconut, soybean, or fish (menhaden) oils. A fourth diet was used as a control. On d 37 to 45 postbreeding, gilts were slaughtered and numerous fetal and ovarian …
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Impacts of Placental Growth Factor Deficiency and of Preeclampsia on Brain Development and Function
… all human pregnancies. In many PE pregnancies, maternal plasma is low in the placentally-produced angiokine “placental growth factor” (PGF). Offspring of PE (PE-F1) compared to uncomplicated pregnancies have higher risks for hypertension, cognitive impairment, and stroke. However, mechanisms …
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Feto-Maternal Exosome Characterization, Trafficking and Function During Pregnancy and Parturition
… and are attributed by senescence-associated feto-maternal signaling via exosomes. Oxidative stress in utero, most likely due to increased metabolic activity of the fetus, induces cellular senescence of the fetal membranes. We have reproduced this model in vitro to show human amnion epithelial …
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Preeclampsia Link to Gestational Hypoxia
… and downstream adverse effects on the fetus. Maternal adverse effects include the angiogenic imbalance that promotes maternal endothelial dysfunction, and adverse effects on the offspring include fetal growth restriction, which is not only a major driver of perinatal morbidity, but also …
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Diagnosi prenatale non invasiva di malattie monogeniche attraverso la ricerca e l'isolamento di cellule e DNA fetale nel sangue materno
… and cell-free fetal DNA (cffDNA) found in the maternal circulation. The presence of fetal cells in the maternal circulation was first documented by 1893 when the fetal cells were found in pregnant women died for eclampsia. The Fetal erythroblasts (NRBC) from the maternal circulation have been …
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Vascular Effects of Low-Molecular Weight Heparin in Pregnant Women at High-Risk of Preeclampsia
… dilation (FMD), compared to controls. Baseline plasma and urine levels of placental growth factor (PlGF) were significantly lower in high-risk women compared with controls. These findings demonstrate that pregnant women at high-risk of PE exhibit impaired endothelial function prior to the …
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The Impact Of Continuous Prenatal And Early Postpartum Maternal Vitamin D Supplementation On The Vitamin D Status Of Exclusively Breastfed Infants
… in knowledge exists regarding best practices in maternal vitamin D supplementation during pregnancy and lactation that will yield adequate infant vitamin D levels. The objective of this study was to identify the combined effect of maternal prenatal and postnatal vitamin D supplementation on …
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Vitamin D during Pregnancy
… neonatal outcomes, (2) the association between maternal plasma vitamin D concentration and dietary intake, and (3) the prevalence of vitamin D deficiency/ insufficiency during pregnancy and the contribution of vitamin D metabolites to estimate vitamin D. This dissertation attempts to address …
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