Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 44 for “"maternal obesity"”.
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Folic Acid Intake, Maternal Obesity and Neural Tube Defects
<p>"Objectives:" To investigate whether maternal obesity before pregnancy is a risk factor of delivery of an infant with neural tube defect (NTD) and to study relationships between folic acid intake during the periconceptional period and the risk of NTD in overweight and non-overweight women.</p> …
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Maternal Obesity During Pregnancy: Cardiovascular Outcomes for Mother and Baby
The prevalence of obesity has increased significantly over the last 30 years such that it is now more common worldwide to be overweight or obese than normal weight. As a result of this, increasing numbers of women are entering pregnancy overweight or obese. Obesity during pregnancy is associated …
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The impact of maternal obesity on vascular and metabolic function throughout pregnancy.
Maternal obesity increases the risk of numerous maternal and fetal complications of pregnancy. Women were recruited at booking for antenatal care. Each subject was examined in the first, Second and third trimester of pregnancy as well as twelve weeks post partum. Using non invasive techniques …
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Examining the placenta’s role in neurodevelopment in the context of maternal obesity
… health, in particular neurodevelopment. Various maternal exposures, such as psychosocial stress, diabetes, infection, and high body mass index (BMI) are associated with higher risks of impaired neurodevelopment in the offspring. One third of women in the United States are affected by maternal …
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Intergenerational effects of early life programming: the role of glucocorticoids and maternal obesity
… lifestyle in modern society, the prevalence of obesity is increasing, in association with problems such as type 2 DM, hypertension, fatty liver, atherosclerosis and the metabolic syndrome. Obesity during pregnancy is linked to problems such as gestational diabetes, hypertension and early …
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Exploring the impact of maternal obesity on offspring renal morphology and later life health
… environments in early life including both maternal under and over-nutrition predisposes individuals to similar adverse traditionally adult onset diseases such as the metabolic syndrome. Epidemiological observations and animal models have highlighted that early life exposure to maternal …
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Fetal origins of cardiovascular dysfunction in an ovine model of maternal obesity in pregnancy
Obesity prevalence has reached epidemic proportions worldwide, including in women of reproductive age. Studies in humans and animal models have shown that exposure to obesity during pregnancy increases the cardiometabolic disease risk in the offspring, independent of genetic and postnatal …
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The effect of maternal obesity/GDM and metformin intervention on maternal, placental and fetal health
… placental extracellular vesicles (EV) in fetal-maternal communication, with their microRNA (miRNA) content affecting maternal metabolism and potentially the fetus. Overall, it is well-established that obese and glucose-intolerant pregnancies have short- and long-term health consequences for …
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Prenatal exposure to maternal obesity and SFLT-1 overexpression and cardiovascular function in the adult offspring
… from what fetus experienced while in utero. The obesity epidemic has led to the evaluation of the effect of a high fat nutritional environment on fetal programming. Conversely, recent studies have shown that the maternal prepregnancy weight is a strong independent risk factor for preeclampsia. …
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Placental (Mal)Adaptation in Maternal Obesity: Immune-Mediated Regulation of Placental Nutrient Partitioning and Fetal Growth
Global rates of obesity continue to rise, leading to increased numbers of women entering pregnancy obese. Maternal obesity is an established risk factor for metabolic complications during pregnancy and can programme the offspring for elevated risk of non-communicable diseases. Obesity is also …
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Exploring the sex-specific programming of cardiovascular disease by maternal obesity and assessing potential interventions to the mother
… are overweight or obese. As the prevalence of obesity increases worldwide this includes women of childbearing age. Over half of all women of reproductive age in the UK are currently classed as overweight or obese. Obesity during pregnancy is known to have a negative impact on maternal health, …
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A study of the relationship between maternal obesity and child under-nutrition in African women attending a child health clinic in Khayelitsha, Cape Town
Background: Malnutrition, manifesting as obesity in women and under-nutrition in children, is a major public health problem in South Africa. There is a multitude of epidemiological evidence reflecting the extent and health effects of these problems, specifically among the African communities. …
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Role of obesity and gestational diabetes mellitus status on the expression of kisspeptin, inflammatory markers and other endocrine signals, and their correlation with foetal outcomes and placental structure
Background: Maternal obesity and gestational diabetes mellitus (GDM) are associated with short and long-term health risks for the mother and child. The placenta produces hormones, including steroids and cytokines, that influence maternal glucose control. Current literature links kisspeptins with …
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Bioenergetic and Metabolic Signatures of Maternal Overnutrition in the Offspring Heart
The growing global incidence of obesity among women of childbearing age has concerning implications for offspring longitudinal health outcomes. In human populations, maternal obesity is associated with a heightened predisposition of offspring towards cardiometabolic disease, whilst hearts of mice …
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Discourses pertaining to, and lived experiences of, 'Maternal Obesity' (Body Mass Index (BMI) ≥ 30) and Gestational Diabetes Mellitus/Type Two Diabetes Mellitus in the pregnancy and post-birth period.
… as ‘high risk’ due to the co-existence of ‘maternal obesity’ (BMI ≥ 30) and Gestational Diabetes Mellitus (GDM)/Type Two Diabetes Mellitus (T2DM) in pregnancy. This is examined in the context of medico-scientific/public health/ popular media discourses pertaining to ‘maternal …
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Intrauterine effects of maternal weight dynamics
Maternal obesity, and weight gain during or after pregnancy, are associated with adverse perinatal outcomes, as well as long-term cardiometabolic disease in the mother and offspring. Previous studies have demonstrated an association between maternal obesity and cardiovascular maladaptation to …
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The effect of metformin intervention on the programming of cardiometabolic health in offspring of obese pregnancy
Obesity and/or diabetes during pregnancy is associated with obesity, metabolic and cardiovascular disease in the offspring. Clinically relevant interventions are required to break the transgenerational cycle of obesity. Metformin is used to treat GDM in the UK and RCTs are investigating metformin …
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An investigation into whether an exercise intervention during pregnancy can prevent the programming of cardiovascular disease in the offspring of obese mothers
… many years to come. Adverse exposures, such as maternal overnutrition, in the early life environment increase the risk of traditionally adult-onset diseases such as cardiovascular disease and type 2 diabetes adding greatly to the next generation’s burden of disease. Studies in animal models …
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Characterizing the Factors Associated with Women’s Adherence to Institute of Medicine Gestational Weight Gain Guidelines and Assessing a Possible Role for Mobile Health through the Evaluation of a Pregnancy-Specific Application SmartMoms Canada
… to an intrauterine environment affected by maternal obesity and excessive gestational weight gain (GWG) pose several adverse short- and long-term health risks to infants. Excessive GWG and maternal obesity are of high priority to public health across many nations. Improving maternal and …
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Manipulating Embryonic Development and Endometrial Function in Ruminants
… studies was performed to examine the effects of maternal obesity on the preimplantation conceptus and endometrium. Exposure to maternal obesity in utero affects offspring development at the postnatal, adolescent, and adult stages of development; however, its impacts on early embryogenesis are not …
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