Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"maternal hyperglycemia"”.
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Dietary resistant starch improved maternal glycemic control in Goto-Kakizaki rat
Treatment for maternal hyperglycemia is limited on account of safety concerns for fetus. Our previous work has shown that inclusion of resistant starch in the diet decreases body fat accumulation in rodents, increases GLP-1 at both the gene expression level and plasma levels, and improves glucose …
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Regulation of glucose transporters in sheep placenta
… immuno-signal was predominantly localised to maternal villous and endometrial tissue. By late gestation oGLUT1 mRNA was most strongly localised to maternal syncytiotrophoblast and villous tissue, whereas oGLUT3 was predominantly localised to fetal trophoblast cells. Placental oGLUT expression …
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Dissecting the Functional Impacts of Non-Coding Genetic Variation
… with two related complex traits: gestational hyperglycemia and fetal adiposity. At the genomic locus associated with maternal hyperglycemia, we found that genetic variation in regulatory elements altered the expression of the HKDC1 gene. Furthermore, we demonstrated that HKDC1 phosphorylates …
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The early origins of obesity: the importance of prenatal vs postnatal environment.
There is growing evidence that maternal obesity, maternal hyperglycemia or maternal intake of diets high in fat, sugar or total calories during pregnancy and lactation is associated with an increased risk of obesity and metabolic diseases in the offspring. The majority of studies to date, however, …