Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 22 for “"maternal exposure"”.
-
Preconception maternal exposure to Nippostrongylus brasiliensis transfers protection against Nb to her offspring
… and associations have been made between maternal helminth infection and altered immune responses to childhood diseases and vaccinations. This shows that helminth-modified maternal immunity may imprint on early offspring immune development in-utero or through breast milk in the form of …
-
An investigation into the effect of maternal exposure to nicotine and copper on neonatal lung development
… smoke, despite awareness of the implications of exposure for themselves and those around them. Campaigns for the promotion of effective tobacco legislation and awareness are continuously being confronted by the tobacco industry’s reluctance to put the health of their consumers before company …
-
The Albanian Cycle of Victimisation: Exploring the Pathways Between Maternal Exposure to Violence and Early Child Development
… Objectives: This study presents novel data on maternal exposure to violence, wellbeing, maternal parenting practices, and child development in Tirana, Albania. The dissertation specifically aims to: (1) explore the relationship between exposure to violence, social support, and mental well-being …
-
Maternal Exposure to Prostaglandin E2 Affects Hippocampal Synaptic Plasticity in Mice Offspring -A Link to Autism Spectrum Disorder
… involved in early healthy brain development. Exposure to environmental risk factors such as air pollutants, infections, and drugs such as acetaminophen during early pregnancy have shown to impact PGE2 levels and have all been linked to Autism Spectrum Disorders (ASDs). Our previous studies …
-
The role of folic acid supplementation on exencephaly induced by maternal exposure to sodium valproate in the TO mouse
… occurrence of NTD resulting from teratogenic exposure. The objectives of this study were to determine the susceptible stages for the induction of NTD by maternal treatment with WA and to investigate how FA could rescue embryos from NTD. A single dose of 400 mg/kg of vaiproic acid was …
-
Maternal Exposure to Violence and Child Malnutrition in LMICs: A Cross-Sectional, Population-Based Study in Conflict-Affected Northern Uganda
Maternal Exposure to Violence and Child Malnutrition in LMICs: A Cross-Sectional, Population-Based Study in Conflict-Affected Northern Uganda Background: Violence against women by an intimate partner is a serious human rights and public health concern, especially in low-and-middle-income countries …
-
A systems approach to determine how Toxoplasma gondii Infection causes neuropsychiatric disease
… acquired T. gondii infection, or for maternal T. gondii infection induced immune activation, to cause psychoneurological disease. The studies described herein, using LCMS (Liquid chromatography–mass spectrometry) demonstrate that adult acquired infection alters the neurochemistry and …
-
Metal exposure in non-occupationally exposed pregnant women of Western Australia and contribution of environmental sources
… pollution is a growing global concern and human exposure has been associated with increased chronic and acute health effects even at low metal concentrations (Hu et al., 2006; US EPA, 2007; Rice et al., 2010; UNEP, 2010). Sensitive members of the population, such as neonates, children and …
-
A Preliminary Investigation into Orofacial Clefts in the Central and Western Regions of Saudi Arabia
… assessed through measuring the distribution of maternal genotypes and alleles according to exposure/no-exposure environmental factors. <br/>Results: The prevalence of NSOFC in government hospitals in the Western and Central regions of Saudi Arabia was 1.17/1000 births. <br/>Environmental risk …
-
Geostatistical Models for Exposure Estimation in Environmental Epidemiology.
… associations between health outcomes and exposure to environmental pollutants benefit from measures of exposure made at the individual level. In this thesis we consider geostatistical modelling strategies aimed at providing such individual-level estimates. We present three papers showing …
-
The neuroendocrine and molecular mechanisms underlying stress-induced maternal effects in the threespine stickleback
Non-genetic maternal effects occur when offspring phenotype is influenced non-genetically by a mother’s phenotype. Exposure of mothers to external stressors, for example, can influence the expression of a wide array of offspring traits essential for survival, including growth, morphology, and …
-
Influence of risk perceptions and social context on working for water herbicide sprayers' Personal Protective Equipment (PPE) compliance in the Western Cape of South Africa
The exposure of workers and farmers to herbicides in middle- and low-income countries is an important public health issue with a significant negative impact on their short- and long-term health status. Besides the possible acute effects, long term exposures to low doses of herbicides leads to …
-
Mothers transfer information via eggs: effect of mothers' experience with predators on offspring
… their offspring via hormonally-mediated maternal effects. In this study, offspring of mothers that had been exposed to a predator during oogenesis (experimental) were compared to offspring of mothers that had not been exposed to a predator (control). I measured the consequences of …
-
Bayesian treed distributed lag models
… there is interest in regressing an outcome on exposures observed over a previous time window. This frequently arises in environmental epidemiology where either a health outcome on one day is regressed on environmental exposures (e.g. temperature or air pollution) observed on that day and …
-
Assessing fetal topoisomerase IIα as a mechanism of in utero benzene toxicity in generating double-stranded DNA damage in CD-1 mice
… epidemiological evidence has shown that benzene exposure during pregnancy is associated with increased infant leukemias after birth. It is hypothesized that these leukemias are being initiated in utero by benzene exposure during pregnancy. The metabolite 1,4-benzoquinone (BQ) specifically …
-
Placental epigenetic modifications and development in valproic acid-induced teratogenesis
… is an anti-epileptic and a teratogen. In utero exposure to VPA is associated with congenital malformations and neurodevelopment disorders. VPA exerts its teratogenic effects through epigenetic dysregulation, which interferes with tissue development and function. Evidence suggests that VPA can …
-
Individual and Interactive Effects of Maternally- and Trophically-Derived Mercury on Early Amphibian Development
… effects of environmentally relevant Hg exposure routes acting at various early life stages in amphibians. By collecting amphibians in the field at the Hg-contaminated South River, VA, I confirmed that amphibians exhibiting different life histories and occupying different ecological …
-
Three essays on the environment and health in cities
… or income, so it is necessary to understand how exposure to various environmental factors might affect fetal health. In contrast to the U.S. where air quality regulations have been implemented since the 1960's, I also observe air pollution in Nairobi, the capital of Kenya and home to 3.1 million …
-
Premature aging of the lungs of the offspring induced by maternal nicotine exposure during gestation and lactation: protective effects of tomato juice
… with normal fetal and neonatal lung development. Maternal cigarette smoke or nicotine exposure produces adverse effects in the lungs of offspring, these include; intrauterine growth retardation, low birth weight, premature birth, reduced pulmonary function at birth, and a high occurrence of …
Page 1 of 2