Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"mastocytoma"”.
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Characterizing The Effect of Dasatinib On Anti-Tumor Immune Response and Exploring The Potential of Combining Targeted Therapy and Immunotherapy In A C-Kit Mutant Mastocytoma Model
… <p>In this study, we show in the c-KIT mutant mastocytoma P815 mouse model that the therapeutic effect of the c-KIT inhibitor dasatinib is substantially dependent on the anti- tumor T cell response. Even though the direct effect of dasatinib on antigen-driven T cell expansion is inhibitory, …
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The Treatment of Solid Tumours with Complete Freund's Adjuvant
… and found to increase survival in both the P815 mastocytoma and 4T1 mammary cancer models. CFA treatment was not, however, found to be effective in the CT26 colorectal carcinoma and the DEN-induced Hepatocellular carcinoma. Combination therapy with CFA and anti-CTLA-4, which blocks the inhibitory …
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The Treatment of Solid Tumours with Complete Freund's Adjuvant
… and found to increase survival in both the P815 mastocytoma and 4T1 mammary cancer models. CFA treatment was not, however, found to be effective in the CT26 colorectal carcinoma and the DEN-induced Hepatocellular carcinoma. Combination therapy with CFA and anti-CTLA-4, which blocks the inhibitory …
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The role of topoisomerase II in amsacrine resistance
… at 33°C) cell-cycle mutant 21-Fb of the murine mastocytoma cell line, P815- The sensitivity of arrested 21-FB cells to amsacrine decreased –less than two-fold in cell survival experiments when compared to proliferating cells. In contrast, DNA breakage and stimulation of protein-DNA complex …
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Novel peptide antigens provide insights into the recognition process by T cells
… 2C was raised against the Ld-expressing P815 mastocytoma cell line. About twenty years ago, a peptide called p2Ca was identified by acid extraction from BALB/c thymus tissue as a peptide that mediated reactivity between the 2C T cell clone and Ld-expressing target cells. While p2Ca has been …