Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"mast cell tumor"”.
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Determining the Roles of Q-SNAREs in Mast Cell Tumor Necrosis Factor Exocytosis
… evidence accumulates on the contributions of mast cell function to the development of allergic disorders, cardiovascular and neurological pathologies, and cancers, there is a growing recognition of the importance of mast cell-derived TNF to mast cell-mediated pathophysiology. However, our …
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Correlation of HAS2-associated gene duplications with biological aggressiveness of mast cell tumors in Chinese Shar-Pei dogs
… a protein associated with angiogenesis and tumor cell motility in multiple human and canine neoplasms. Cutaneous mucinosis in Shar-Pei has been associated with gene duplications upstream of the hyaluronic acid synthase 2 gene (HAS2). The objective of this study was to evaluate the …
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Surgical margin evaluation in veterinary medicine: an assessment of canine skin shrinkage and histopathologic reporting of canine mast cell tumors
When cutaneous mast cell tumors (MCT) are removed and evaluated for histopathology, the tissue undergoes many changes. Initially the mass is removed with planned surgical margins, which are a measure of grossly normal tissue around the tumor border. The cut margins are marked so that the …
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The use of optical coherence tomography to enhance surgical margin assessment for canine mast cell tumors
… majority of surgical instrumentation used for tumor excision created a high-scattering region with local architectural disruption. Blood pooling was visible as a high- scattering layer overlying tissue with normal architecture. Only the scalpel blade created a focal, low-scattering area …
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Identification of the presence and activity of the JAK-STAT pathway in canine solid tumors
Background: The JAK-STAT pathway is a cellular signaling pathway, which acts normally in humans and animals in the control of multiple important functions. Dysregulation of this pathway has been identified in human cancers, as well as a limited number of veterinary cancers. Objectives: The aims of …
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INSIGHTS ON THE CROSSTALK BETWEEN THE IMMUNE SYSTEMAND CANCER: IMMUNE CHECKPOINT MOLECULES AND LYMPHOIDPOPULATIONS ASSESSMENT IN CANINE ROUND CELL TUMORS
… and sentinel lymph nodes (SLNs) of dogs with mast cell tumors (MCTs). Regarding PD-L1, the project evaluated the expression of the surface membrane protein (mPD-L1) by means of flow cytometry (FC), mRNA by real-time qPCR, and soluble protein (sPD-L1) plasmatic concentrations by competitive …