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Showing 1 to 1 of 1 for “"masked antibodies"”.
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FROM ANTIBODY-DRUG CONJUGATES TO MASKED ANTIBODIES: BIOPHYSICAL INSIGHT FOR THE RATIONAL DESIGN OF FUTURE THERAPIES
Monoclonal antibodies have become a major class of therapeutics over the past twenty-five years and, during this time, many successful antibody scaffolds have been based on wild-type humanized and human sequences of the immunoglobulin G isotype 1 (IgG1) subclass. In the past, several mutations have …