Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"manganese superoxide dismutase"”.
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Role of Manganese Superoxide Dismutase in Chemotherapy-induced Oxidative Stress
… cell lymphoma is mediated by an increase in manganese superoxide dismutase (MnSOD) protein expression and accumulation of hydrogen peroxide (H₂O₂). Findings indicate that the rapamycin-induced cytostatic effect is characterized by increased levels of MnSOD and H₂O₂, and is necessary for the …
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Novel Molecules that Regulate Bone Formation and Bone Resorption
… activity, iron-sulfur cluster formation, and manganese superoxide dismutase activity. We found that DOR is an important regulator of osteoblast differentiation. In addition, a single nucleotide polymorphism (SNP) in the promoter of human DOR gene associated with plasma levels of the bone …
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The effects of cellular quiescence on the antioxidant defense enzymes of bovine embryonic lung fibroblasts: a survey
… is still unclear. Free radicals such as the superoxide radical (O₂⁻) and the hydroxyl radical (OH⁻), formed in biological oxidation reactions may be responsible for cellular aging. Because of the high reactivity of the O₂⁻ and the OH⁻ they can produce extensive damage to lipids, proteins, and …
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The involvement of free radicals in the casual mechanism of Motor Neurone Disease
… of the free radical detoxif'ing enzymes superoxide dismutases (copper/zinc superoxide dismutase (SOD I), manganese superoxide dismutase (SOD2), glutathione peroxidase (GSHPx) and catalase (CAT) at the site of motor neurone loss (i.e. the anterior horn in the spinal cord) showed a …
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Engineering Estrogen Receptor-Based Gene Switches and a Superoxide Dismutase for Therapeutic Applications
… E. coli selection system based on resistance to superoxide toxicity was used in a directed evolution approach to enhance the catalytic efficiency of a rationally designed mutant manganese superoxide dismutase enzyme exhibiting greatly reduced product inhibition and low catalytic efficiency …
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Fall-Kontrollstudie zur Bedeutung von Polymorphismen im MnSOD-Gen für die Sensibilisierung auf para-Phenylendiamin (PPD)
… phase of allergic contact dermatitis to PPD. Manganese superoxide dismutase (MnSOD) is one of the primary enzymes that directly scavenge potential harmful oxidizing species. Several genetic polymorphisms in the MnSOD gene have been associated with various disease risks. A single nucleotide …
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Allergic bronchopulmonary aspergillosis in cystic fibrosis: prevalence, clinical complications, diagnosis and influence on the outcome
… the development of ABPA. Soluble enzymes such as manganese superoxide dismutase and soluble glycoproteins from hyphae with certain antigenic fractions have shown to have increase activities and reacted with sera of ABPA patients. The advantages of WSSH A. fumigatus antigen are being a multivalent …
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Effect of benzylglucosinolate on signaling pathways associated with type 2 diabetes prevention
… resistance expressed by the up-regulation in manganese superoxide dismutase (MnSOD) and detoxification enzymes; to modulate autophagy by induction of BECLIN1 and down-regulation of the mammalian target of rapamycin complex 1 (mTORC1) pathway; and to promote cell cycle arrest and DNA damage …
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The exercise-induced expression of heat shock proteins in human skeletal muscle : the role of evaluated muscle and core temperature and the influence of training status
… increases in either HSP27, aB-crystallin, manganese superoxide dismutase (MnSOD) protein content or the activity of superoxide dismutase (SOD) and catalase. When examining baseline protein levels, HSC70, HSP27 and aB-crystallin appeared consistently expressed between subjects whereas HSP70 …