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Showing 1 to 2 of 2 for “"mammary tumorsphere"”.
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Identification of Novel HIF1A Target Genes That Regulate Tumor Progression and Metastasis
… <p>Our lab has established primary mammary tumor epithelial cells (MTECs) from late stage carcinomas originating in PyMT+; Hif1a floxed mice. These MTECs were exposed to either Adenovirus-beta-gal or -Cre to create wild-type (WT) and knockout (KO) cells, respectively. Deletion of …
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Identification and Characterization of Her2/Neu-Transformed Breast Cancer Stem Cells
… we cultivated primary tumor cells and grew tumorspheres under non-adherent condition. Cells capable of forming tumorspheres retained ability of self-renewal and capacity for initiating tumors that recapitulate the original heterogeneity, which resembled normal stem cells within normal …