Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"mammary differentiation"”.
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Molecular determinants of mammary differentiation and breast cancer progression
The mammary epithelium is an architecturally complex tissue comprising of multiple cell lineages. Development and maintenance of this tissue are carefully orchestrated by balancing stem and progenitor cell self-renewal and differentiation. The mammary epithelium must also endure the successive …
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New methods to study human mammary development and breast cancer
… cancer is fundamentally a disease of aberrant differentiation. Breast cancers arise from within the normal architecture of the mammary gland and resemble normal mammary epithelial cell types on a molecular and gene expression level. Many tumors become dependent on the signaling pathways that …
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New technologies and methodologies for the study of human mammary epithelial differentiation and development
The mammary gland is unique among human tissues in that the bulk of its development occurs postnatally, under hormonal control. The gland consists of an epithelium that expands dramatically during puberty and pregnancy, and is the site of breast cancer initiation. Important connections between …
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Proteomic Analysis of Mammary Epithelial Cell Development
… used to investigate the protein profile of the mammary epithelial cell (MEC) through different stages of mammary development. The HC11 cell line was used to investigate protein changes between undifferentiated and differentiated MEC, which represent the pregnant and lactating states of the …