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Showing 1 to 1 of 1 for “"mammalian surface display"”.

  1. Conformational engineering of human chemokine receptors and HIV-1 Env using deep mutational scanning

    Heredia, Jeremiah D.University of Illinois at Urbana-Champaign2020

    … were selected in tissue culture for surface expression, binding to conformation-specific antibodies, binding to a chemokine, and binding to the HIV-1 surface glycoprotein Env. Using these landscapes, I identified that the chemokine CXCL12 binds asymmetrically in the CXCR4 …

    uiuc Repository record