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Showing 1 to 1 of 1 for “"malignant osteolysis"”.

  1. Investigating procaspase-3 as a potential therapeutic target in canine osteosarcoma

    … and furthermore, greater expression is seen in malignant canine osteoblasts than normal osteoblasts. Exposing cells to PAC-1 results in the activation of procaspase-3 to caspase-3, increased caspase-3 catalytic activity, and induction of apoptosis in osteosarcoma cells. The greatest degree of …

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