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Showing 1 to 2 of 2 for “"maleless"”.

  1. Investigation of the roX RNAs and the RNA Helicase MLE in Dosage Compensation in Drosophila melanogaster

    … least five proteins, including the RNA helicase Maleless (MLE). MLE contains two highly conserved double stranded RNA binding domains (DRBDs) at the N terminus. We investigated the roles of the roX RNAs and MLE helicase through experiments using classical genetic methods to generate and analyze …

    duke Repository record for Investigation of the roX RNAs and the RNA Helicase MLE in Dosage Compensation in Drosophila melanogaster (opens in a new tab)

  2. RNA Helicase 1 interacts with an ABCRNAi Transporter: Genetic Interactions with haf-6

    … domains. rha-1 is orthologous to the Drosophila maleless gene(MLE), an essential component of the dosage compensation machinery that leads to a two-fold increase in transcription of genes located on the single X chromosome of males in comparison to the transcription rate of homologous genes …

    ku Repository record for RNA Helicase 1 interacts with an ABCRNAi Transporter: Genetic Interactions with haf-6 (opens in a new tab)