Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 41 for “"male infertility"”.
-
Male Infertility: The Process to Seeking Treatment
Infertility has an effect on both males and females. Current literature focuses on women rather than men. The purpose of this study was to gain an understanding of the process that adult males go through from deciding to conceive to seeking treatment for male-factor infertility. A qualitative …
-
The association between sperm aneuploidy and male infertility: Screening, aetiology and possible routes to alternative therapy
… start a family are infertile. The many causes of infertility include genetic defects that can be single gene, multifactorial or chromosomal (including Y deletions, karyotype abnormalities and gamete aneuploidy). This thesis is concerned with the association between infertility and increased sperm …
-
Depletion of docosahexaenoic acid (DHA) and arachidonic acid causes male infertility by disrupting both secretory granule biogenesis and adherens junction assembly in testis
… disease, CHD, sub-optimal fetal development and male infertility. The long chain omega-3 docosahexaenoic acid (DHA) and omega-6 arachidonic acid (ARA) are highly unsaturated fatty acids (HUFAs) preferentially enriched in the sn2 position of membrane phospholipids and ARA is abundant in tissues …
-
Examining the (patho)physiology of physiologically relevant ligands present in the male and female reproductive tracts
… this has yet to advance to the diagnosis of male infertility. One of the main reasons for this is the lack of understanding of the physiological regulation and function of the highly complex sperm cell. Understanding the critical roles of different proteins in maintaining sperm function is …
-
Male inguinal hernia repair with mesh. Short- and long-term results and the question of infertility.
… has been proposed to increase the incidence of male infertility due to inflammatory obstruction of the structures of the spermatic cord. Aims: To compare the Lichtenstein and the TEP operation techniques regarding short- as well as long-term results. To assess the risk of male infertility …
-
Obesity-Induced Alterations in Sperm Quality, Testicular Morphology, and Extracellular Vesicle Localisation in Male Mice
Background: Infertility is a recognised reproductive health issue affecting individuals worldwide. An increase in male infertility has been reported, with concurrent evidence of declining semen quality. Obesity is a major contributor to infertility, with obese men presenting with decreased …
-
Investigating the effect of phosphodiesterase inhibitors on human sperm motility and function
… increasingly apparent that the main cause of infertility is male factor. Today, ICSI represents most treatment which itself demonstrates the severity of male infertility. This may include problems with sperm concentration, motility and/or morphology. Sperm motility defects are associated with …
-
Meiotic defects in infertile men
… (ICSI) has revolutionized the treatment of male infertility, concerns have been raised regarding the risk of chromosomal abnormalities in pregnancies derived from ICSI. Studies on sperm from infertile men have suggested that this population may produce higher rates of aneuploid sperm. Thus, …
-
Andrological Methods of Predicting the Pregnancy Outcome of an <i>in vitro</i> Fertilization Program
… IVF is now used to treat several types of infertility, including male factor and idiopathic infertility. However, IVF is time consuming, costly, unpredictable, and often yields a low pregnancy rate. Thus, it would be valuable to devise laboratory procedures for better prediction of IVF …
-
Changes In The Testes Following Spinal Cord Injury and The Attenuating Effects of Licofelone
… changes in a multitude of organ systems. Male infertility is one such complication that is particularly devastating because the patient population is predominantly young men. Our lab has previously shown that the blood testis barrier breaks down after spinal cord injury. This dissertation …
-
Investigation of Ring Finger Protein 8 in Mammalian Physiology and Pathogenesis
… DNA DSB repair defects, genomic instability, male infertility, immunodeficiency and cancer development at the organism level.
-
The role of Cdyl and CDY in mammalian spermatogenesis
… CDY is thought to have an important role in male fertility and spermatogenesis. However, human studies have not yet been able to directly implicate CDY in male infertility. Even though mouse Cdyl is not located on the Y chromosome, it is the closest known mouse homologue of human CDY and is …
-
The effect of sperm apoptosis, Reactive Oxygen Species (ROS) and semen sample handling on sperm parameters and Assisted Reproductive Technology (ART) outcomes
… knowledge and clinical practice regarding male infertility, especially in relation to the potential sources and clinical impact of sperm apoptosis and reactive oxygen species (ROS) in the context of assisted reproductive technology (ART). This thesis encompasses three independent studies, …
-
Regulation of SNARE function during sperm capacitation to promote the acrosome reaction
Infertility is a tragedy for millions of couples worldwide. According to the World Health Organization, the male factor alone accounts for over one third of total infertility. There are various causes of male infertility but defective acrosomal exocytosis is perhaps one of the biggest contributors …
-
The role of dietary arachidonic acid and docosahexaenoic acid in preventing the phenotype observed with highly unsaturated fatty acid deficiency
… DHA and consists of ulcerative dermatitis, male infertility, gastrointestinal ulcers, and hepatic lipidosis. New insight on specific AA and DHA roles was established through dietary prevention of HUFA deficiency phenotype. The absence of a D6D isozyme had to be assessed before further …
-
Mechanism of Spermatogonial Stem Cell Regulation by ETV2
Spermatogenesis is the process through which male germ cells give rise to spermatozoa. Spermatogenesis is initiated from spermatogonial stem cells (SSCs) which self-renew or differentiate to give rise to differentiated progenies of germ cells. Hence understanding of SSC biology is essential to …
-
Diverse outcomes of homologous recombination in the human Y chromosome
… in allelic homologous recombination, the male-specific region of the Y (MSY) - the only haploid portion of the nuclear genome - does not. It does, however, engage in non-allelic homologous recombination. In this thesis, I examine modes and outcomes of non-allelic homologous recombination …
-
Magnetic Micromotors in Assisted Reproductive Technology
… which is one of the most prevalent causes of male infertility. Second, as synthetic carriers of fertilized oocytes (zygotes) towards the realization of non-invasive intrafallopian transfer, representing a novel alternative to the current keyhole surgery (laparoscopy) approach to achieve early …
-
Living with infertility: an exploratory study of men’s experience
Research on the infertility realm is mostly dominated by the female experience and on gender differences. Despite the fact that half of the infertility issues are associated with men, research on the male experience remains limited. There has recently been a change since more studies have been …
-
Novel method of selecting human spermatozoa for <em>In </em><em>Vitro </em>fertilization
Traditionally, the diagnosis of male infertility is based on semen analysis when semen volume, sperm concentration, motility and morphology are evaluated. These characteristics help to assess how many spermatozoa are capable to get through the natural barriers of the female reproductive tract such …
Page 1 of 3