Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"male genital tract"”.
-
Studies on immunity in the male genital tract
The male genital tract is a major site of HIV acquisition and transmission. It is an obvious site for inducing immune responses to candidate HIV vaccines, to prevent infection or halt the spread of the virus. There are relatively few published studies characterising T cells in the male genital …
-
The distribution of plasminogen activator in the male genital tract
The blood of man is rich in plasminogen, the inactive precursor of plasmin, a protease (Astrup, 1956a); the most characteristic action of plasmin is the digestion of fibrin, i.e. fibrinolysis. Many tissues, including the prostate (Rasmussen and Albrechtsen, 1960a), contain substances which can …
-
Characterizing various aspects of the male genital tract barrier function and immunity
… modes of HIV transmission. Voluntary medical male circumcision (VMMC) is associated with a 60% reduced risk of HIV acquisition through heterosexual intercourse. However, uncircumcised men comprise approximately 70% of the male population worldwide, implying that although an effective …
-
Male genital tract versus blood HIV-1 compartmentalization and selection: the first step of the transmission bottleneck?
… between these two populations: HIV-1 from the genital tract of the donors: where viruses are on their way to transmission to a new recipient. Importantly, numerous prior studies have shown that there is compartmentalization of HIV-1 populations between the general circulation and the genital …
-
Equilibrative Nucleoside Transporter Mediated Drug Disposition Across the Blood-Testis Barrier
… a problem for therapeutic disposition to the male genital tract, which may allow viruses or cancer to persist in the testis, and impedes the development of male contraceptives and fertility treatments. Drug transporters present at the basal and apical membranes of testicular epithelial cells …
-
Investigating the susceptibility of foreskin myeloid cells to ex vivo HIV infection
… acquisition and spread especially through the male genital tract (MGT)1–4. Several authors have shown the human foreskin to be an effective mucosal effector site with heterogenous populations of innate and adaptive immune cells, that are permissive to HIV infection5–8. In support of this, …
-
Functional Expression of ABC Transporters at Blood-tissue Barriers: Relevance to Antiretroviral Drug Tissue Distribution
… several tissue compartments i.e., the brain and male genital tract have been identified as viral reservoirs which can harbor actively replicating HIV-1 virus (Chan, 2005;Dahl, et al., 2010;Smith, et al., 2007;Solas, et al., 2003). In addition to harboring the virus, several studies have observed …
-
Sperm Competition and the Function of Masturbation in Japanese Macaques (Macaca fuscata)
Male masturbation or sexual-auto stimulation is well documented in humans. This study dealt with the occurrence of masturbation in non-human primates in general, and in Japanese macaques (Macaca fuscata) in particular, from the perspective of behavioural ecology. In an interspecific comparison of …
-
MORPHOLOGICAL FEATURES OF THE REPRODUCTIVE ORGANS IN DOMESTIC SPECIES IN RELATION TO WATER MOVEMENT CONTROL, HYPONUTRITION AND ENVIRONMENTAL INFLUENCES IN FETAL AND PREPUBERTAL LIFE, AND METABOLISM REGULATOR FACTORS.
… is important in every reproductive moment of a female mammal life. Rapid transcellular water movements are facilitated by AQPs that increase plasma membrane permeability. The results from my research showed that AQP-mediated water movement between the intraluminal, interstitial, and capillary …