Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"major histocompatibility complex class II"”.
-
Identification and characterization of a chicken major histocompatibility complex class II[beta] gene promoter
<p>The major histocompatibility complex (MHC) contains a variety of genes. Among them, the class II genes encode proteins involved in antigen presentation to helper T cells, a key step in initiating immune responses. The regulation of class II gene expression has been extensively studied in …
-
Genetics of disease resistance: Molecular characterisation of the major histocompatibility Complex Class II genes in Bos species of different origin : A thesis submitted in partial fulfilment of the requirements for the Degree of Master of Science at Lincoln University
… systems. In this context, the important role the Major Histocompatibility Complex (MHC) proteins play in immune responses would suggest that improved understanding of the MHC genes is vital to understanding and manipulating genetic resilience to infectious diseases. The genes of MHC are highly …
-
Kinetics and Intracellular Pathways Required for MHC Ii-Peptide Loading and Surface Expression of a Hapten-Protein Conjugate in Murine Macrophage
… of foreign proteins in the context of the major histocompatibility complex class II molecule (MHC II). The sequence of events that lead to the formation of these MHC II-peptide complexes has been termed antigen processing, and several specific questions related to this pathway remain …
-
Imaging innate immune cell behaviour in lymphoid organs
… with adaptive immune cells, for example via major histocompatibility complex class II (MHCII) expression for antigen presentation. Secondary lymphoid organs, including lymph nodes (LNs) and Peyer’s patches, are ideal sites for innate-adaptive cellular interactions. Whilst neutrophils migrate …
-
Effects of Spaceflight on Phagocytic Function and Immune-Neural Interaction
… phagocytic activity, bacteria clearance, Major histocompatibility complex class II (MHC II) expression and cFos in the paraventriculuar nucleus (PVN) were characterized. We then examined the effects of body-only proton radiation exposure on phagocytic activity to determine the role played …
-
Regulation of Adaptive Immunity in the Lung by the Alveolar Epithelial Type II Cell and Surfactant Protein a
… or asthma. The alveolar epithelial type II cell and its secretory product, surfactant protein A (SP-A), have been linked to roles in adaptive immunity in the lung. The discovery that type II cells constitutively express major histocompatibility complex class II (MHC II) suggested that …
-
Do respiratory epithelial cells ‘remember’ early life microbial exposure through epigenetic changes?
… causes lasting changes in the levels of major histocompatibility complex class I (MHC-I) and II (MHC-II) on the surface of AECs. Furthermore, as seen through histone modifications, I confirmed that RSV infection causes lasting epigenetic changes in AECs, including in the promoters of …