Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 39 for “"magnetic resonance spectroscopic imaging"”.
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Line scan proton magnetic resonance spectroscopic imaging
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Nuclear Engineering, 1995.
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Accelerated J-resolved proton magnetic resonance spectroscopic imaging
… challenge of conventional 1H-MRSI is that resonances from different molecules overlap with one another in the crowded chemical shift frequency spectrum, which will lead to great difficulties in separating different resonances and accurate detection of specific molecules. J-resolved 1H-MRSI …
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Model-based reconstruction of magnetic resonance spectroscopic imaging
Magnetic resonance imaging (MRI) is a medical imaging technique that is used to obtain images of soft tissue throughout the body. Since its development in the 1970s, MRI has gained tremendous importance in clinical practice because it can produce high quality images of diagnostic value in an ever …
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Subspace estimation for subspace-based magnetic resonance spectroscopic imaging
This Thesis was approved for publication on 2016-04-15 at 14:08.
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Ultrafast magnetic resonance spectroscopic imaging: technical development and applications
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-08-01
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Magnetic resonance spectroscopic imaging using parallel transmission at 7T
Conventional magnetic resonance spectroscopic imaging (MRSI), also known as phase-encoded (PE) chemical shift imaging (CSI), suffers from both low signal-to-noise ratio (SNR) of the brain metabolites, as well as inflexible tradeoffs between acquisition time and spatial resolution. In addition, …
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Fast magnetic resonance spectroscopic imaging using RF coil arrays
Conventional Magnetic Resonance Spectroscopic Imaging (MRSI) suffers from both low signal-to-noise (SNR), as well as long acquisition times. The development of high-fidelity gradient coils has opened opportunities for fast k-space encoding schemes that are already used in structural imaging. At the …
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A subspace approach to high-resolution magnetic resonance spectroscopic imaging
… profiles from the human body noninvasively, magnetic resonance spectroscopic imaging (MRSI) has been recognized as a powerful tool for in vivo metabolic studies. However, research and clinical applications of in vivo MRSI have been progressing more slowly than expected. The main reasons for …
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Spectral estimation with spatio-spectral constraints for magnetic resonance spectroscopic imaging
Magnetic resonance spectroscopic imaging (MRSI) is a promising tool to acquire in vivo biochemical information, and spectral estimation (quantification) of MRSI data is an important step towards quantitative studies. Although a large body of work has been done on spectral estimation over the past …
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Prior -Information -Driven Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging
… including reduced field-of-view dynamic imaging, T2 mapping, MR thermometry, and MR spectroscopic imaging.
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Further development of magnetic resonance spectroscopic imaging using subspace-based models
Magnetic resonance spectroscopic imaging (MRSI) is a powerful, non-invasive imaging modality capable of providing in vivo measurements of chemical distributions within an object. This makes it an ideal tool for metabolic studies in clinical and research settings; yet, despite more than four decades …
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Development of Magnetic Resonance Spectroscopic Imaging Methods to Assess Tumour Metabolism
… nuclei such as 15N and 13C have been proposed as magnetic resonance spectroscopic imaging (MRSI) agents for investigating metabolism, perfusion and pH in tumours. However, the sensitivity of direct detection is limited by the low gyromagnetic ratios of these nuclei. Sensitivity can be increased by …
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Towards high-resolution magnetic resonance spectroscopic imaging: spatiotemporal denoising and echo-time selection
Magnetic resonance spectroscopic imaging (MRSI) enables acquisition of spatial-spectral nuclear spin distributions. Compared to conventional MRI, the additional spectral information provides a powerful tool for in vivo study of biological tissues. However, considerable practical challenges, which …
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High resolution magnetic resonance spectroscopic imaging of the brain from 3T to 7T
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-08-01
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Magnetic resonance spectroscopic imaging with 2D spectroscopy for the detection of brain metabolites
While magnetic resonance imaging (MRI) derives its signal from protons in water, additional biochemical compounds are detectable in vivo within the proton spectrum. The detection and mapping of these much weaker signals is known as magnetic resonance spectroscopy or spectroscopic imaging. Among the …
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Denoising for deuterium magnetic resonance spectroscopic imaging based on posterior-score-guided subspace modeling
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2025-12-01
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Development of pulse sequences for hyperpolarized 13C magnetic resonance spectroscopic imaging of tumour metabolism
Metabolic imaging with hyperpolarized 13C-labeled cell substrates is a promising technique for imaging tissue metabolism in vivo. However, the transient nature of the hyperpolarization - and its depletion following excitation - limits the imaging time and the number of excitation pulses that can be …
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Investigating brain metabolite levels in adolescents living with HIV using atlas-based magnetic resonance spectroscopic imaging (MRSI)
… studies are predominantly based on single voxel magnetic resonance spectroscopy (MRS) in younger children, with inconsistent findings. We aimed to develop atlas-based pipelines for analysing MRSI data to examine whether there are differences in brain metabolite levels between adolescents with …
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Sequence-phase optimal (SPO) [d̳e̳l̳t̳a̳]B₀ field control for lipid suppression and homogeneity for brain magnetic resonance spectroscopic imaging
… and improve brain metabolite spectra in proton spectroscopic imaging. A rapidly reconfigurable 32-channel, local-multi-coil-shim-array is used to enhance lipid suppression and narrow metabolite linewidth in magnetic resonance spectroscopic imaging (MRSI) of the brain. The array is optimally …
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Identifying The Immune Related Metabolic Properties of Pancreatic Cancer Using Nuclear Magnetic Resonance Spectroscopy and Dynamic Magnetic Resonance Spectroscopic Imaging With Hyperpolarized Pyruvate
… a tumor’s response to immunotherapy.</p> <p>Magnetic resonance (MR) is an intrinsically low sensitivity technique, but dynamic nuclear polarization allows one to increase the MR signal by five orders of magnitude. As described by the Warburg effect, even in the presence of an ample amount of …
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