Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"magnetic activated cell sorting (MACS)"”.
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Development of a MACS-based strategy for isolating rare cell populations from animal tissue for transcription factor studies
Two major challenges in studying specific cell populations of embryos or adult organs are: a) getting the sample sufficiently pure for the cells of interest; b) getting sufficient quantities of these cells. Current methods used for isolating specific cell populations from tissues are either too …
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Transcriptional profile of c-kit positive cardiac stem-progenitor cells (c-kitpos eCSCs) isolated from the four chambers of the adult human heart
… population of resident (endogenous) cardiac stem cells (eCSCs). They express the stem cell factor receptor c-kit, are distributed throughout the myocardium, are clonogenic, self-renewing and multi-potent, in that they differentiate into the 3 main cardiac lineages; cardiomyocytes, smooth muscle …
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Microfluidic Concentration Gradient Generation and Integrated Magnetic Sorting of Microparticles
… their feature size similar to that of biological cells, have great potential for cell manipulation and interrogation. On the other hand, the process of drug discovery involves vast amount of tests of candidate drug molecules with cells, and hence requires intensive manipulation and interrogation …
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Deficiency in Parkinson's Disease risk gene CD38 as it relates to glial function: dysregulation of astrocyte genes and bioenergetics as a result of CD38 deficiency
… system (CNS) inflammatory status and means of cellular energy production typically precede pathological indications. In the brain, CD38 expression is most enriched in astrocytes in BG regions, including substantia nigra, midbrain, and striatum. However, it is not known how CD38 deficiency may …
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Investigation of a pancreatic derived progenitor cell population for use in regenerative medicine
… insulin replacement therapy. Pancreatic stem cells or progenitor cells have been proposed as an attractive therapy either as a source of cells for in vitro expansion and differentiation to islets for transplantation, or as a direct in vivo cell therapy. Cellular senescence is a state of …
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Regenerationspotenzial CD133+-hämatopoetischer Progenitorzellen der humanen Nabelschnur beim Nierendefekt im Mausmodell
… Publikationen zur Transplantation - von mittels MACS hoch aufgereinigten - humanen Stammzellen in murine Nieren. Um das Integrationsverhalten und das Regenerationspotenzial CD133-positiver humaner Zellen genauer zu erforschen, transplantierten wir CD133-positive Progenitorzellen der human …