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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 115 for “"macular degeneration"”.

  1. Immunogentetic pathways in age related macular degeneration

    Goverdhan, SrinivasUniversity of Southampton2008

    soton Repository record

  2. Advanced imaging biomarkers in age-related macular degeneration

    Μαρκόπουλος Κωνσταντίνος, Markopoulos Konstantinos2026

    Η ηλικιακή εκφύλιση της ωχράς κηλίδας, είναι μία κύρια αιτία σημαντικής μείωσης της όρασης παγκοσμίως, ενώ η επίπτωση της εκτιμάται ότι θα αυξηθεί σημαντικά. Η αναγνώριση πρώιμων βιοδεικτών που θα σημάνουν την αυξημένη πιθανότητα μετάπτωσης από πρώιμα σε πιο προχωρημένα στάδια της νόσου, που …

    athens Repository record

  3. TGF-beta 1 PATHWAY AND AGE-RELATED MACULAR DEGENERATION

    FISICHELLA, VINCENZOUniversità degli studi di Catania2017

    … mimics pathologic conditions such as age-related macular degeneration (AMD) using amyloid-beta (Abeta) oligomers, and assess the effect of TGF-beta 1. Furthermore a topical formulation of transforming growth factor 1 (TGF-beta 1) was developed; and TGF-beta 1 ocular pharmacokinetics profile was …

    catania Repository record

  4. Effects of combination therapies on age-related macular degeneration

    Lo, DavidBoston University2013

    Age-related macular degeneration (AMD) is the most common cause of vision loss in America for people over the age of 60. Due to damage to the retina, symptoms normally include blurred central vision, difficulty reading, and seeing shadows. While there is no cure for the disease, there are …

    bu Repository record

  5. Image-Based Biomarkers in Retinal Disease: Applications in Macular Degeneration

    Boretsky, AdamThe University of Texas Medical Branch at Galveston2016

    … analyze image-based biomarkers of retinal degeneration. A combination of imaging and enhancement techniques thatincluded confocal scanning laser ophthalmoscopy, white light fundoscopy, optical coherence tomography and adaptive optics were used for the in vivo data collection. To achieve …

    utmb Repository record

  6. Topical Clear Aqueous Nanomicellar Formulations for Age-Related Macular Degeneration

    Alshamran, MeshalUniversity of Missouri--Kansas City2020

    … Among the back of the eye disorders, age-related macular degeneration (AMD) is one of the major ailments responsible for blindness worldwide. There is currently no effective treatment available to cure AMD completely. Anti-VEGF therapy is currently considered the treatment of choice. However, it …

    umkc Repository record

  7. Rare genetic variants in patients with age-related macular degeneration

    Duvvari, M.R.S.l. : s.n.2015

    Contains fulltext : 148918.pdf (Publisher’s version ) (Open Access)

    radboud Repository record

  8. Visual field and structural alterations in age-related macular degeneration

    Acton, Jennifer H.Aston University2010

    … of patients with varying degrees of agerelated macular degeneration (AMD). The relationships between structure and function were investigated for both standard and short-wavelength automated perimetry (SWAP). Factors known to influence the measure of visual field progression were considered, …

    aston Repository record

  9. Novel nanocarriers to improve drug delivery for age-related macular degeneration

    Sikder, SadiaUniversity of Missouri--Kansas City2021

    … of life of millions worldwide. Age-related macular degeneration (AMD) is ranked third on a global scale as one of the major back-of-the-eye disorders being responsible for blindness in elderly patients over 60 years. As there is no efficacious cure to completely prevent AMD, the invasive …

    umkc Repository record

  10. Investigating the genetic and molecular basis of age-related macular degeneration

    Stanton, Chloe MayThe University of Edinburgh2012

    Age-related macular degeneration (AMD) is the leading cause of blindness worldwide, affecting an estimated 50 million individuals aged over 65 years. Environmental and genetic risk-factors contribute to the development of AMD. An AMD-risk locus on chromosome 10q26 spans two genes, ARMS2 and HTRA1, …

    edinburgh Repository record

  11. Connexin43 as a novel therapeutic target in age-related macular degeneration

    Guo, XiaopengResearchSpace@Auckland2014

    Age-related macular degeneration (AMD) is the major cause of blindness in the elderly. There is currently no cure for AMD although several risk factors have been implicated in the pathogenesis and progression of the disease. These include oxidative stress, inflammation and vascular changes. …

    auckland-ms Repository record

  12. Improving face perception and quality of life in age-related macular degeneration

    Lane, Joanne Rachel2018

    … and good quality of life. Age-related macular degeneration (AMD) is a progressive eye condition that damages central vision required to see faces clearly. This thesis aims to investigate potential means to improve quality of life in AMD, via a two-pronged approach. The first prong …

    aus-cath Repository record

  13. Improving face perception and quality of life in age-related macular degeneration

    Lane, Joanne Rachel2018

    … and good quality of life. Age-related macular degeneration (AMD) is a progressive eye condition that damages central vision required to see faces clearly. This thesis aims to investigate potential means to improve quality of life in AMD, via a two-pronged approach. The first prong …

    anu Repository record

  14. Potential of endothelial progenitors to reverse choroidal atrophy during age related macular degeneration

    McKeown, StuartQueen's University Belfast2020

    Pre-clinically ECFCs have already demonstrated a high potential for revascularisation in a number of models, this makes them an attractive candidate for a number of conditions where impaired blood flow is a factor affecting recovery. However, it is still important to consider the pathology that …

    qu-belfast Repository record

  15. Genetics of age-related macular degeneration and Stargardt disease in South African populations

    Baard, JohannesDivision of Human Genetics2016

    … points of particular note have emerged regarding Macular Degenerations (MD) : (i) that more than 58% of juvenile MD, notably Stargardt Disease (STGD) , in Caucasian populations may have the underlying causative genetic defect identified , while only 1 1 % of the similar phenotype in indigenous …

    cape-town Repository record

  16. Drug Loaded Multifunctional Microparticles for Anti-VEGF Therapy of Exudative Age-related Macular Degeneration

    Zhang, LeileiThe Ohio State University2012

    <p>Age-related macular degeneration (AMD) is the leading cause of vision loss and blindness in people over age 65 in industrialized nations. The exudative AMD accounts for only 10% to 20% of AMD cases, but causes 80 to 90% of cases with severe vision loss related to AMD. The current intravitreal …

    ohiolink Repository record

  17. Iron-induced Complement Dysregulation in the Retinal Pigment Epithelium: Implications for Age-Related Macular Degeneration

    Li, Yafeng2015

    Age-related macular degeneration (AMD), typically manifesting as a loss of central vision in elderly persons, is a leading cause of blindness in highly developed nations. AMD is a multifactorial disease associated with aging, oxidative stress, complement dysregulation, dsRNA toxicity, among many …

    penn Repository record

  18. DOSE RANGING STUDY OF LUTEIN SUPPLEMENTATION IN ELDERLY WITH AND WITHOUT AGE RELATED MACULAR DEGENERATION

    Moura, Fabiana Fonseca2004

    Age-related macular degeneration (AMD) is the leading cause of blindness among people over the age of 65. Epidemiological studies have indicated that people with a high intake of two dietary carotenoids, lutein and zeaxanthin that accumulate in the human macula, are at a reduced risk of AMD. …

    maryland Repository record

  19. Separation and Purification of a Monoclonal Antibody for use in Patients Suffering from Wet Macular Degeneration

    Abbas, Syed, Sulharia, Amaad, Clary, Wesley, Del Bianco, Marcus, Guillen, Dario, Harder, Tanaka, Henrique Israel, Luis, Lopez, Joel, McMahon, Adam M., Schmidt, Monica, Worsnop, Stephanie, Zanette, RikelliUniversity of Nevada, Reno2015

    Novel process designs were created in an effort to optimize the efficiency of monoclonal antibody separation and purification for an industrial process. A base case was established that utilized common protein separation techniques such as cation exchange chromatography, anion exchange …

    unr Repository record

  20. Diet Patterns and Incident Age-Related Macular Degeneration in the Atherosclerosis Risk in Communities (ARIC) Study

    Dighe, Shruti; 0000-0002-6654-521XState University of New York at Buffalo2018

    M.S.

    buffalo Repository record

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