Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"macropinosome"”.
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CBL and CBL-B Dictate CSF-1R Endocytic Traffic and Signaling in Macrophages
… to regulate CSF-1R endocytosis and traffic to macropinosome in macrophages. Macrophages were derived from mice knocked out for Cbl, Cbl-b or the double knock out (DKO). DKO macrophages hyperproliferated, matching the severe myeloproliferative disorder observed in DKO mice. The CSF-1R and …
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Role of Bacterial Effectors SopD and SopB in Pathogenicity of Salmonella enterica serovar Typhimurium.
… cells. SopD promotes membrane sealing and macropinosome formation, events that may have important consequences for efficiency of bacterial cell entry in vivo. Furthermore, we demonstrate that SopD is recruited to the invasion site membranes through the phosphatase activity of SopB, …
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Sphingomyelinases and Lysosomal Trafficking in Ebolavirus Entry
… outer leaflet, resulting in ASM-dependent macropinosome formation. Because EBOV enters via a macropinocytosis-like mechanism, the role of ASM in infection was assessed. Specific ASM chemical inhibitors and RNA interference (RNAi) were used to show that ASM was important for EBOV-GFP …