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Showing 1 to 20 of 34 for “"macrophage migration"”.

  1. Studies on Macrophage Migration in Pathological Contexts

    Yates, MatthewUniversity of East Anglia2014

    Macrophages play key roles following nerve injury releasing cytokines and chemokines thought to be involved in the development and maintenance of neuropathic pain. ATP is a transporter of chemical energy, but can also act as an extracellular signalling molecule that signals through purinergic …

    east-anglia Repository record

  2. ROLE OF P50 NF-KB IN MACROPHAGE MIGRATION

    TOTARO, MARIA GRAZIAUniversità degli Studi di Milano2010

    Tumor Associated Macrophages (TAM) and lipopolisaccharide- (LPS)-tolerant macrophages share several characteristics, such as a massive accumulation of the p50 NF-B homodimer in the nucleus and the incapacity to express strong inflammatory programs (eg. impaired TNF production) in response to …

    milano Repository record

  3. The Role of Macrophage Migration Inhibitory Factor in Osteoarthritis

    Rowe, Meredith AustinWake Forest University2015

    ABSTRACT

    wfu Repository record

  4. Role for Macrophage Migration Inhibitory Factor in Multiple Sclerosis

    CAVALLI, EUGENIOUniversità degli studi di Catania2017

    Il fattore di inibizione della migrazione dei macrofagi (MIF) è una citochina proinfiammatoria che svolge un ruolo importante nella patogenesi di numerosi disordini infiammatori e autoimmuni. Come tale, è un obiettivo terapeutico interessante per il trattamento di questi disturbi. Diversi dati …

    catania Repository record

  5. Expression of Macrophage Migration Inhibitory Factor in Behçet's disease

    인, 성일2011

    PURPOSE: Macrophage migration inhibitory factor (MIF) is a unique protein, participating in inflammation, immune response, and cell growth. Previous reports showed that MIF-173 G>C polymorphism or the MIF-794 [CATT]5-8 polymorphism and haplotypes containing these variants were associated with an …

    ajou Repository record

  6. Molecular mechanisms of the unconventional secretion of macrophage migration inhibitory factor (MIF)

    Merk, MelaniePublikationsserver der RWTH Aachen University2008

    Macrophage migration inhibitory factor is a pro-inflammatory cytokine that plays a pivotal role in the pathogenesis of inflammatory disease such as septic shock and rheumatoid arthritis. The release of MIF from inflammatory cells is a common feature in these diseases, and a correlation between the …

    aachen Repository record

  7. A Leishmania ortholog of macrophage migration inhibitory factor modulates host macrophage responses

    Kamir, DanielaPublikationsserver der RWTH Aachen University2008

    … of the pro-inflammatory pleiotropic cytokine, macrophage migration inhibitory factor (MIF). These two MIF-like sequences show 22% sequence identity when aligned with human MIF, and are most likely the result of gene duplication. The Lm1740MIF and Lm1750MIF genes (58% identity) are expressed in …

    aachen Repository record

  8. Dissecting the impact of macrophage migration inhibitory factor (MIF) on host immune response

    Park, MyeongseonVirginia Tech2018

    Macrophage migration inhibitory factor (MIF) has been implicated in mediating both innate and adaptive immune responses in inflammatory and infectious diseases. The sequence and structure of MIF is highly conserved across the avian phylogeny, which underlies high sequence homology and functional …

    vt Repository record

  9. The Involvement of Interleukin-1 Receptor-Associated Kinase-1 (IRAK-1) as a Critical Modulator of Macrophage Migration

    Gan, LuVirginia Tech2010

    Macrophage migration, an essential component of many biological processes and pathologic conditions, is mediated by integrated cellular signaling processes and cytoskeleton rearrangement. Recent advances indicate that the innate immunity signaling process plays a key role in the regulation of …

    vt Repository record

  10. Expression des Zytokins macrophage migration inhibitory factor (MIF) in ischämischem Endothel und Bedeutung bei der Rekrutierung endothelialer Progenitorzellen (EPCs)

    Simons, David2010

    aachen Repository record

  11. Die prognostische Bedeutung von Macrophage Migration Inhibitory Factor (MIF) und seinem endogenen Antagonisten Gremlin-1 im Plasma von Patienten mit kalzifizierter Aortenstenose

    Brunner, Julia2021

    tuebingen

  12. Macrophage migration inhibitory factor führt in humanen Endothelzellen zur Aktivierung der SRC-Kinase, der PI-3-Kinase und des MAP-Kinase Signalwegs

    Retzmann, DeniseUniversität Ulm

    ulm-diss Repository record

  13. The Role of Immunological Receptors CD74 and CD44 in Association with the Macrophage Migration Inhibitory Factor (MIF) on Human Breast Cancer Derived Cells

    Al ssadh, HussainUniversity of Essex2016

    … synergy and are susceptible to the effect of the macrophage migration inhibitory factor (MIF). MIF is a 12.5 kDa chemokine-like inflammatory mediator, whose ligand is the transmembrane receptor CD74. Recent data suggests that CD74 is involved in proinflammatory responses and tumorigenesis but …

    essex Repository record

  14. Splenic Regulation Of Macrophage Activity In Mice Infected With Listeria Monocytogenes

    Cavender, Nancy Ann

    … The regulatory role of the spleen over macrophage activation in mice was investigated. The macrophage migration inhibition test was used to measure in vitro macrophage activity. Macrophages from splenectomized, infected mice were shown to have increased migration and therefore increased …

    mo-state Repository record

  15. LATE PROTECTIVE EFFECTS OF NETRIN-1 AND ADENOSINE A2B RECEPTOR ACTIVATION IN THE MURINE ACETAMINOPHEN HEPATOTOXICITY MODEL

    Duan, LuqiUniversity of Kansas2020

    … translocation; in contrast, netrin-1 promoted macrophage migration and liver regeneration. Its receptor adenosine A2B receptor (A2BAR) was highly induced at late time points and blocking its receptor could remove its late protective effects, indicating that netrin-1 through its receptor A2BAR, …

    ku Repository record

  16. The Identification of the MCHR-1 in J774A.1 Macrophages and The Effect of Melanin-concentrating Hormone on a 3T3-L1 Adipocyte-J774A.1 Macrophage Co-Culture

    Johnston, BrockSUNY Brockport, Honors College2023

    … acrophages in our laboratory. First, the J774A.1 macrophage line was acquired. Eventually, successful macrophage culturing technique was learned. Then, I asked whether theses J774A.1 macrophage expressed the Mchr1 gene and MCH receptor protein as well as whether this cell line responded at all to …

    brockport Repository record

  17. Therapeutic Approaches to Insulin Resistance and Type 2 Diabetes

    Leonard, SiobhanNational University of Ireland Maynooth2015

    … have suggested a role for this receptor in macrophage infiltration into adipose tissue to augment insulin resistance through an unknown mechanism. Overexpression studies revealed GPR21 to be a constitutively active receptor, which couples Gαq type G proteins leading to the activation of the …

    maynooth Repository record

  18. Tumor microenvironmental control of metastasis : effects of the immune cells and physical forces on cell migration

    Li, Ran, Ph. D. Massachusetts Institute of TechnologyMassachusetts Institute of Technology2017

    … can influence metastasis. Specifically, macrophage, one of the most abundant tumor-associated stromal cell types, has been shown to assist cancer cell invasion. However, exactly how macrophages affect the different aspects (e.g. speed and persistence) of cancer cell migration, especially …

    mit Repository record

  19. Cannabinoid Modulation of Chemotaxis of Macrophages and Macrophage-like Cells

    Raborn, Erinn Shenee2014

    … reported to modulate functional activities of macrophages. It is recognized that macrophages express primarily the CB2 cannabinoid receptor, but recent studies indicate that its expression is differential in relation to activation state with maximal levels occurring when cells are in …

    vcu Repository record

  20. CDK9 inhibitor treatment during the innate inflammatory and regenerative response in a zebrafish model of cardiac injury

    Kaveh, AryanThe University of Edinburgh2021

    Neutrophils and macrophages are crucial effectors and modulators of cardiac repair following myocardial infarction (MI). Sustained neutrophilic inflammation is detrimental for cardiac repair and associated with adverse MI outcomes. An attractive therapeutic strategy to treat acute inflammatory …

    edinburgh Repository record

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