Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"macrophage inflammatory response"”.
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Modulating the Inflammatory Response of Macrophages on Biomaterial Surfaces
The foreign body response is an inflammatory response to implanted materials and poses significant challenges for biomaterials-based medical applications, often leading to the degradation or fibrous encapsulation of an implanted device. The host response is largely dictated by the proteins that …
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Metabolic Regulation of Gene Expression through Differential Histone Acylation: The Regulation and Function of Histone Crotonylation
… methods, I next studied the impact of Kcr in the macrophage inflammatory response, a classic model of signal-dependent gene activation. Through bioinformatics analysis of RNA-seq and ChIP-seq of macrophages in various conditions, I established that increased histone Kcr leads to enhanced …
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The immunological role of cell wall components from diverse Mycobacterium tuberculosis clinical isolates in regulating HIV-1 replication in human macrophages
… potentially due to bioactive Mtb lipids engaging macrophage surface receptors, thus triggering signaling pathways which activate human transcriptional factors (hTF) and production of inflammatory cytokines capable of activating HIV-1 transcription. This work investigated the hypothesis that …