Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"macromolecular dynamics"”.
-
Protein Dynamics and its Correlation to Protein Activity and Stability
… is to investigate the role of fast protein dynamics (picosecond timescale) in enzyme activity and stability, and specifically to test the hypothesis that enzyme activity and stability are inversely related by their internal dynamics. Activity Dynamics (flexibility) 1/Stability In order to …
-
Probing Collective Motions and Hydration Dynamics of Biomolecules by a Wide Range Dielectric Spectroscopy
Studying dynamics of proteins in their biological milieu such as water is interesting because of their strong absorption in the terahertz range that contain information on their global and sub-global collective vibrational modes (conformational dynamics) and global dynamical correlations among …
-
Two -Photon Standing Wave Fluorescence Photobleaching With Application to the Study of Chromatin Motion
… diffusion is connected to the nucleosomal dynamics on much smaller lengthscales, this may provide a way to assay biochemical activity in vivo based on larger scale macromolecular dynamics observed via fluorescence microscopy.
-
Integration of Structural Methods to Characterize the Dynamics of Macromolecular Complexes
… the structure, and function, of various macromolecular complexes beyond the conventional low-energy, singular state approach. To do this, we extend existing methods and create new approaches catered for the study of large-scale macromolecular dynamics. Here, we characterize the …
-
Plasticity of the Nuclear Pore Complex Revealed With Proteomics
… are performed by the concerted action of macromolecular assemblies. These protein machines rarely have permanent, invariable structures. Instead, the subunits forming the macromolecular assemblies exchange between free and bound states, changing the composition, conformation and function …