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Showing 1 to 2 of 2 for “"mTORC1 regulation"”.

  1. Regulation of mTORC1 by phosphatidic acid: mechanism and structural insight

    … 1. The mammalian target of rapamycin complex 1 (mTORC1) is regulated, in part, by the endogenous inhibitor DEPTOR. However, the mechanism of DEPTOR regulation with regard to rapid mTORC1 activation remains unknown. In collaboration with Dr. Mee Sup Yoon, I discovered that DEPTOR is rapidly and …

    uiuc Repository record for Regulation of mTORC1 by phosphatidic acid: mechanism and structural insight (opens in a new tab)

  2. Involvement of Gdap1 In The Regulation of Mtorc1 Activity In A Drosophila Mliv Model

    … mechanistic target of rapamycin complex 1 (mTORC1), is responsible for maintaining metabolic homeostasis by sensing nutrient and energy levels within the cell to promote or inhibit translation and autophagy accordingly. In the childhood neurodevelopmental disorder Mucolipidosis type IV …

    uthsc Repository record for Involvement of Gdap1 In The Regulation of Mtorc1 Activity In A Drosophila Mliv Model (opens in a new tab)