Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"mRNP complexes"”.
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Messenger Ribonucleoprotein (Mrnp) Complexes: Proteomic and Functional Analysis
We provided the evidence that both microtubules and actin filaments are required for the proper localization of FMRP-RNP particles. Furthermore, FMRP associates with both microtubule- and actin-based motors, kinesin-1 and myosin Va. In order to unambiguously identify the detailed molecular …
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Investigating the function and mechanistic control of processing bodies in early Drosophila melanogaster development
… argued that the ability of multiple individual mRNP complexes to condense into granules may not always provide additional function beyond the formation of single mRNP complexes. In this thesis, I utilise the genetically, chemically, and physically manipulatable model system of *Drosophila …
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Nanobody-Based Interactomic Studies of Single Transcripts During mRNA Maturation
… transcripts and each other to form dynamic mRNP complexes. While there are many core, essential mRNP factors, the pathways governing mRNA maturation are not uniform, and different transcripts can be associated with mRNP complexes of dramatically different composition or kinetics. To date …
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The PUF proteins in Trypanosoma brucei
… mRNAs which associated with PUF proteins in mRNP complexes were identified. PUF5 for example, selectively binds to mRNAs encoding for amino acid transporters in bloodstream form cells. Attempts to identify PUF interaction partners have so far failed. The effect of PUF proteins on global …
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Stress-Induced Targeting of Molecular Chaperones In The Yeast Saccharomyces Cerevisiae
… disassembly or conversion of these enigmatic mRNP complexes. Taken together, the work presented in this dissertation serves to better understand the eukaryotic stress response by illustrating the importance of subcellular-chaperone localization in key biological processes.