Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"mRNA targeting"”.
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FMRP dependent synaptic delivery of messenger RNA
… the regulatory role of FMRP involved in synaptic mRNA delivery. In chapter 1, the molecular mechanism of local protein synthesis and synaptic mRNA delivery and its roles in Fragile X syndrome and learning and memory are introduced. In chapter 2, my data demonstrated that FMRP can facilitate mRNA …
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The Role of miR-126/126* in Microenvironmental Regulation of Cancer Metastasis
… the guiding strand of the miRNA duplex into the mRNA-targeting RNA induced silencing complex (RISC), both strands of the miR-126 RNA duplex are maintained at a similar level and suppress Sdf-1α expression independently. </p><p>Collectively, we have determined a dynamic process by which the …
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Biochemical purification and functional characterization of the She RNP complex from S. cerevisiae
Asymmetric mRNA localization is a widely used mechanism to sort cell fate determinants in development. In the budding yeast Saccharomyces cerevisae ASH1 (for 'asymmetric synthesis of HO') mRNA localization to the tip of the growing bud leads to targeting of Ash1p to the daughter cell nucleus prior …