Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"mRNA polyadenylation"”.
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Prediction of mRNA polyadenylation sites in the human genome and Mathematical modeling of alternative polyadenylation
Messenger RNA (mRNA) polyadenylation plays many important roles in the cell, such as transcription termination, mRNA stability and transportation, and mRNA translation in eukaryotic cells. A large number of human and mouse genes have multiple polyadenylation sites (referred to as poly(A) sites) …
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Chemical Reporters for Bacterial Pathogenesis and Beyond
… to previous RNA reporters allows labeling of mRNA polyadenylation tails. In conclusion, I have developed chemical reporters for the cell selective labeling of bacteria in the presence of mammalian cells, a chemical reporter for protein AMPylation, and a chemical reporter for RNA synthesis and …
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Bioinformatics study of mammalian MRNA polydenylation
Messenger RNA polyadenylation is one of the key post-transcriptional events in mammalian cells, which have influences on many aspects of mRNA metabolism. Several human diseases have been shown to associate with abnormal polyadenylation, highlighting the importance of this process. The availability …
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A bioinformatics framework for RNA structure mining, motif discovery and polyadenylation analysis
… hits. Further, the role played by structure in mRNA polyadenylation was investigated. Polyadenylation is an important step towards the maturation of almost all cellular mRNAs in eukaryotes. Studies have identified several cis-elements besides the widely known polyadenylation signal (PAS) element …