Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"mRNA modifications"”.
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ARCHITECTURE AND RNA RECOGNITION BY THE EUKARYOTIC M6A METHYLTRANSFERASE COMPLEX
RNA modifications are critical post-transcriptional regulators of gene expression, influencing diverse biological functions. Among them, N6-methyladenosine (m6A) is one of the most abundant mRNA modifications and contributes to key cellular processes, including mRNA processing, translation, and …
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Role of m<sup>6</sup>A RNA "reader" YTHDF2 in Mammalian Germ Cells and Early Embryo Development
RNA modifications affect the processing and metabolism of mRNA which ultimately leads to changes in gene expression. Regulation of gene expression is essential for every tissue and every organism, specifically in cell fate determination. N6-methyladenosine (m6A) is one of the most abundant and …
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Transcriptome-wide pseudouridine profiling reveals modification of critical E. coli mRNAs
… of life, and is now known to be present in the mRNAs of diverse eukaryotes. However, the modification was yet to be identified in bacterial mRNAs, and its functional roles remain largely unknown. In Chapter 1, I provide an overview of the structure and function of pseudouridine, focusing on the …