Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"mRNA granules"”.
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Mechanisms of persistent translation arrest following global brain ischemia and reperfusion
… studies, my results indicate that the mRNA granules are ribonomic structures involved with mRNA regulation. This finding is significant because it shifts the focus onto mRNA metabolism and away from ribosomal molecular biology. I have identified new pathways to investigate for …
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Investigation Of Posttranscriptional Regulation After Global Brain Ischemia And Reperfusion Injury
… reperfusion. Previous studies suggested that the mRNA-binding protein HuR may regulate hsp70 mRNA in reperfused neurons through a novel cytoplasmic structure, the mRNA granule. To determine the roles of HuR and the mRNA granule in reperfused neurons and to characterize global translation …
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mRNA localization in Caenorhabditis elegans embryogenesis
… output, post-transcriptional regulation of mRNA is essential for life. As a result, many mechanisms underlying post-transcriptional regulation are highly conserved across the kingdoms of life. As the spatial resolution of microscopy and sequencing assays has increased, mRNA localization has …
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Mechanisms of translation arrest following focal brain ischemia
… formation of subcellular particles involved in mRNA metabolism such as stress granules and mRNA granules. My Background discussion will lead to my hypotheses about mechanisms of prolonged TA following focal brain I/R and the possible effect of diabetes on these mechanisms. In subsequent chapters …