Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 631 for “"mRNA expression"”.
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Molekulare Analyse der mRNA-Expression von Plasma-Prokallikrein
… Rolle. Neuere Arbeiten haben gezeigt, dass PPKmRNA auch außerhalb der Leber exprimiert wird. Daraus ist zu schließen, dass dort ebenfalls PPK-Protein gebildet wird und dass diesem extrahepatischen, gewebeständigen PPK bzw. PK spezielle lokale Funktionen zukommen. Dieser Befund bildet die …
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mRNA-Expression des CRH-Systems in menschlichen schwangerschaftsspezifischen Geweben
… Geburt. <br>In dieser Arbeit wurde die mRNA-Expression von CRH, UCN,CRH-BP sowie der CRH-R1 bzw. 2) an menschlichen schwangerschaftsspezifischen Geweben, die bei Schnittentbindungen gewonnen wurden, mittels RT-PCR untersucht. Dazu wurde eine Gewebebank mit Myometrium, Plazenta, Dezidua, …
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Plasma Volume and Albumin mRNA Expression in Exercise Trained Rats
… training induces an increase in albumin gene expression in relationship to the increase in PV. <strong><em>Methods and Results-</strong></em> 40 adult male Sprague-Dawley rats weighing between 245-350 grams were randomly assigned to one of four groups: cage control (CC); sham exercise 10 …
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mRNA EXPRESSION ANALYSIS OF MIDBRAIN DOPAMINE NEURONS IN RESPONSE TO NICOTINE INTAKE DURING MATURATION
… and memory. Previous studies suggested that the expression of neuroprotective genes was significantly different in the VTA and SN dopamine neurons and nicotine mediated neuroprotection in PD. These studies encouraged us to investigate how nicotine changes the expression of these differentially …
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Immune Response Markers are Prevalent in the mRNA Expression Profile of Maturing Dystrophic Murine Skeletal Muscle
… in DMD could be identified by the global expression of mRNA in maturing dystrophin- and utrophin-deficient mouse (mdx:utrn-/-) muscles. Two potential dystrophic onset mechanisms targeted for analysis were (1) disrupted expression of calcium handling proteins; and, (2) increased expression …
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Regulation of mRNA expression through 3’ UTR sequences of IL6 gene in amino acid-deprived HeLa cells
… Here, it was investigated whether 3’UTR of IL6 mRNA played a role in IL6 induction through cellular stress responses. In the studies with GFP-reporter containing 3’UTR of IL6 mRNA, it was elucidated that 3’UTR contributed to increase of IL6 mRNA after amino acid-starvation, and its motifs seemed …
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Investigation of mRNA Expression of Early Light Inducible Protein (ELIP) under High Light Stress <em>Arabidopsis thaliana</em>.
… what signal(s) may be involved in <em>ELIP</em> expression. My hypothesis is that redox status of the chloroplast photosynthetic electron transport Chain (PETC) and/or chlororespiration may induce <em>ELIP</em> expression. Using the <em>Arabidopsis thaliana immutans (im)</em> chlororespiratory …
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Classification of Neuronal Nicotinic Acetylcholine Receptors in Rat CA1 Hippocampal Interneuron Subpopulations Defined by Calcium-Binding Protein mRNA Expression
… study, the single-cell relative quantitative mRNA expression of three Calcium-binding proteins (CaBPs; calbindin, calretinin, parvalbumin) and eight nicotinic acetylcholine receptor (nAChR) subunits (alpha2-alpha5, alpha7, beta2-beta4) from interneurons from the stratum radiatum or stratum …
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Osteogenesis During Early Healing Around Titanium and Titanium Zirconium Implants: Immunohistochemistry and mRNA Expression of Bone Markers in Miniature Pigs
… transcription. In addition, the level of protein expression can be analyzed by immunohistoflourescence (IHF). A pilot study was performed to evaluate the expression of the osteogenic genes/biomarkers, and the quantity/quality of bone in contact with the implant during the early healing around …
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Attachment Ability and Melanoma Inhibitory Activity mRNA Expression Level Changes in Murine B16-F10 Melanoma Cells Post Nanosecond Electric Pulses
… cells and reverse transcribed into cDNA. The MIA mRNA expression levels were measured using the cDNA temple via quantitative real-time PCR, with β–actin as the internal control. The experiment was repeated three times (n=3). The results show that a single pulse did not affect the cell attachment …
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Establishment and implementation of multiplexed error robust fluorescence in situ hybridization to study spatial mRNA expression in cells and tissues
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-12-01
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The regulation of RANK and RANKL mRNA expression through activation of the JAK2/STAT5a pathway in human breast cancer cell lines ©
… objective of this study is to determine if RANKL mRNA expression is regulated through the JAK/STAT5a pathway by stimulating human breast cancer cell lines, MCF-7 and MDA-MB-231, with prolactin (PRL), epidermal growth factor (EGF) and heregulin-beta1 (HRG-1), all known to activate STAT5a and play …
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The Effects of Metronomic and Maximum-Tolerated Dose Chemotherapy in Colorectal Cancer Angiogenesis: A Combined Approach Using Endoscopic Diffuse Reflectance Spectroscopy and mRNA Expression
… (using diffuse reflectance spectroscopy and mRNA expression) to study the changes in angiogenesis and metabolism in primary colorectal tumors receiving MTD and MET. In Chapter 2, we first developed and validated a miniaturized spectroscopy probe that enabled the longitudinal investigation of …
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Effects of close-up dietary energy strategy and prepartal dietary monensin on hepatic mRNA expression of enzymes involved in glucose and lipid metabolism in transition cows
… to these two different diets on bovine hepatic mRNA expression of enzymes involved in liver adaptive mechanisms during the transition period. The treatments were arranged in a 2 (one-stage CON or two-stage OVER feeding strategy) × 2 (inclusion of 0 or 22g/ton of M) factorial arrangement. The CON …
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Evidence for enhanced oxidative stress in smokers with severe asthma
… by analysing urinary 8-iso-PGF2a and the mRNA expression of the main pro-oxidant (NOX2; NOSs) and anti-oxidant (SODs; CAT; GPX1) enzymes in the airways, in relation to clinical outcomes. Methods Urine and induced sputum (IS) were obtained from severe asthma patients. A bronchoscopy to …
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Entwicklung von Verfahren zur Erkennung individueller Strahlenempfindlichkeit durch Analyse der Expression geeigneter Kandidatengene
… Geweben auf eine Strahlentherapie wichtig. Die mRNA-Expression in DNA-Reparatur-Genen (ATM, APEX1, BRCA1, BRCA2, ERCC1, MDM2, TP53 und TOP3A) von Krebspatienten vor einer Strahlentherapie sollte deshalb als möglicher Biomarker für eine Strahlenüberempfindlichkeit untersucht werden. In diesem …
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Untersuchung des kardialen LIM-Domänen Proteins FHL2 im menschlichen Myokard : Rolle von FHL2 bei der Herzinsuffizienz
… Dazu wurde mittels Northern Blot die FHL2-mRNA Expression im menschlichen insuffizienten und nicht-insuffizienten Myokard analysiert und funktionelle Analysen zur transkriptionellen Aktivität von FHL2 in vitro durchgeführt und der Einfluß von FHL2 auf die Expression eines …
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Effects of lower- and higher- volume resistance exercise on serum testosterone and skeletal muscle androgen receptor content in men : subsequent effects on the mRNA expression of insulin- like growth factor peptide and myostatin in skeletal muscle.
… addition, the testosterone level can alter the expression of insulin–like growth factor and myostatin which are key regulators of muscle protein balance. Higher-intensity resistance exercise in non-resistance-trained participants is known to increase endogenous serum testosterone levels. …
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