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Showing 1 to 1 of 1 for “"mRNA Cleavage and Polyadenylation Factors"”.

  1. SAM Homeostasis Is Regulated by CFIm-Mediated Splicing of MAT2A

    … as a regulator of MAT2A intron detention and intracellular SAM levels. CFIm25 is a component of the cleavage factor Im (CFIm) complex that regulates poly(A) site selection, but we show it promotes MAT2A splicing independent of poly(A) site selection. CFIm25-mediated MAT2A splicing …

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