Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"mFOLD"”.
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DNA Secondary Structure in Human Disease and Gene Regulation
… expansion and disease. Finally, using the Mfold and ViennaRNA programs with thermodynamic paramaters for single-stranded DNA we analyze the ability of the complete human genomic DNA sequence to form stable DNA secondary structures. We find that predicted highly stable DNA secondary …
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RNA secondary structure detection programs with an emphasis on covariance models
… structure tools (CARNAC, miRNAminer, Pfold, Mfold) as well as between Infernal and the primary alignment tool BLAT. CMfinder and Infernal are also compared against each other. RNA secondary structure databases, mainly Rfam and miRBase, are used to provide sequence and alignment data.
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Dna Aptamers Selected Against Wild-Type Helix 69 Ribosomal Rna And Their Implications In Combating Antibiotic Resistance
… optimal secondary structures were predicted by Mfold analysis. Analysis of 120 clones led to the identification of 20 sequences with consensus motifs. Notably, one of the selected DNA ligands (H69DNAapt18) contained a conserved 20-nt hairpin-loop motif with complementarity to the loop region of …
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Biological and functional consequences of polymorphisms in the XPD gene
… in older subjects and in smokers. Localized Mfold structure analysis of the mRNA sequence surrounding the studied SNPs were predicted to alter mRNA secondary structure, which indicated that these SNPs potentially affect local folding and mRNA stability. UVC treatment of cells with wild type …
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Advanced tools for RNA secondary structure analysis
… the aforementioned questions. Among these are MFOLD which produces a subset of all possible structures according to a threshold of structural similarity, SFOLD which samples the structures in a probabilistic fashion and provides a method to identify alternating structures, RNAsubopt to produce …
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XPC Haplotypes Alter DNA Repair Capacity and Levels of Genetic Damage
Xeroderma pigmentosum complementation group C (XPC) is the key recognition factor of DNA damage in global genome nucleotide excision repair (NER). The disease Xeroderma pigmentosum (XP) results from mutations leading to structural defects of the encoding gene and in some instances trace to changes …